Detomidine
別名: Dormosedan
> **Important Guidance for Owners:** * This drug is a potent sedative and should only be used in a professionally supervised setting by individuals familiar with its properties. * Even if your horse appears deeply asleep, they can still react suddenly and kick if startled by loud noises or touch. Always approach sedated horses with caution. * If using the oral gel at home under veterinary direction, wear impermeable gloves to prevent the drug from absorbing through your skin.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Anesthesia
- Analgesia
- Anesthesia
- Analgesia
- Sedation/analgesia
- Analgesia
- Sedation/analgesia
- Sedation/analgesia (Sublingual Gel)
- Marked abdominal pain (not surgical candidates or long transport)
- Sedation/analgesia with butorphanol
- Adjunctive treatment of moderate pain
- Caudal epidural analgesia
- Oral administration when not amenable to injections
- CRI for standing chemical restraint and analgesia (Protocol 1)
給藥方式
可能的副作用
- Initial blood pressure increase (hypertension)
- Profound bradycardia and heart block (AV block)
- Piloerection
- Sweating
- Ataxia
- Salivation
- Slight muscle tremors
- Penile prolapse
- Decreased gastrointestinal motility
注意事項與禁忌
- Preexisting AV or SA heart block
- Severe coronary insufficiency
- Cerebrovascular disease
- Severe respiratory disease
- Chronic renal failure
- > **Clinical Precautions:** * **Shock & Organ Dysfunction:** Use cautiously in animals with endotoxic/traumatic shock, or advanced hepatic/renal disease. * **Stress Factors:** Administer carefully to horses stressed by temperature extremes, fatigue, or high altitude. Consider lower doses in summer heat. * **Gastrointestinal:** Inhibits GI motility; use with prudence in patients treated for intestinal impactions. May mask abdominal pain in colic cases, complicating diagnosis. * **Safety:** Wear impermeable gloves when administering the sublingual gel to avoid human exposure.
藥物相互作用
- Other Alpha-2 Agonists (e.g., xylazine, medetomidine, clonidine): Not recommended to be used together as effects may be additive.
- Anesthetics, Opiates, Sedative/Hypnotics: Effects may be additive; dosage reduction required. Increased risk for arrhythmias with thiopental, ketamine, or halothane.
- Epinephrine: Do not use to treat cardiac effects caused by detomidine, as epinephrine possesses alpha agonist effects.
- Phenothiazines (e.g., acepromazine): Severe hypotension can result.
- Potentiated Sulfonamides (e.g., trimethoprim/sulfa): Fatal dysrhythmias may occur if used with intravenous potentiated sulfonamides.
常見問題
Detomidine用於寵物有甚麼用途？
> **Important Guidance for Owners:** * This drug is a potent sedative and should only be used in a professionally supervised setting by individuals familiar with its properties. * Even if your horse appears deeply asleep, they can still react suddenly and kick if startled by loud noises or touch. Always approach sedated horses with caution. * If using the oral gel at home under veterinary direction, wear impermeable gloves to prevent the drug from absorbing through your skin.
Detomidine對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。