Deferoxamine Mesylate
別名: Desferal, DFO
Your pet is receiving **deferoxamine** because they have ingested a toxic amount of iron (such as human iron supplements or oxygen absorber packets found in food packaging). * **Hospitalization**: This medication must be given by injection, often as a continuous IV drip, so your pet will need to stay in the hospital for monitoring. * **Urine Color Change**: You or the veterinary staff may notice your pet's urine turning a pink or reddish color (often described as 'vin rosé'). **This is normal and expected.** It means the drug is successfully binding the iron and flushing it out through the kidneys. Treatment usually continues until the urine color returns to normal. * **Follow-up**: Even after successful treatment, iron toxicity can cause damage to the stomach and intestines. Monitor your pet closely at home for vomiting, dark tarry stools, or signs of abdominal pain over the next 4 to 6 weeks, as strictures (scar tissue blockages) can sometimes develop.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Severe iron toxicosis
- Severe iron toxicosis
- Severe iron toxicosis
- Severe iron toxicosis
- Severe iron toxicosis
- Severe iron toxicosis
- Ferric ion chelator during treatment of cardiac arrest (experimental)
- Ferric ion chelator during treatment of cardiac arrest (experimental)
給藥方式
可能的副作用
- Allergic reactions (hives, wheezing)
- Auditory neurotoxicity (with chronic, high-dose therapy)
- Pain or swelling at injection sites
- Gastrointestinal distress
- Hypotension, tachycardia, and convulsions (if given IV too rapidly)
- Pulmonary edema (associated with rapid IV administration)
注意事項與禁忌
- Severe renal failure (unless dialysis is used to remove the ferrioxamine complex)
- > **WARNING**: Intravenous administration must be performed slowly (preferably via Constant Rate Infusion). Too rapid IV injection can precipitate severe hypotension, arrhythmias, and shock. * **Pregnancy**: FDA Category C. Has caused skeletal abnormalities in animals at doses just above those recommended for iron toxicity. Use only when benefits outweigh risks. * **Oral Use**: Oral administration is controversial and generally not recommended, as it may increase the amount of iron absorbed from the gut. * **Laboratory Interference**: May cause falsely low values on colorimetric iron assays and falsely high Total Iron Binding Capacity (TIBC) measurements.
藥物相互作用
- Prochlorperazine: Concurrent use may cause temporary impairment of consciousness.
- Vitamin C (Ascorbic Acid): May be synergistic in removing iron, but could lead to increased tissue iron toxicity, especially in cardiac muscle. Use with extreme caution in patients with preexisting cardiac disease.
常見問題
Deferoxamine Mesylate用於寵物有甚麼用途？
Your pet is receiving **deferoxamine** because they have ingested a toxic amount of iron (such as human iron supplements or oxygen absorber packets found in food packaging). * **Hospitalization**: This medication must be given by injection, often as a continuous IV drip, so your pet will need to stay in the hospital for monitoring. * **Urine Color Change**: You or the veterinary staff may notice your pet's urine turning a pink or reddish color (often described as 'vin rosé'). **This is normal and expected.** It means the drug is successfully binding the iron and flushing it out through the kidneys. Treatment usually continues until the urine color returns to normal. * **Follow-up**: Even after successful treatment, iron toxicity can cause damage to the stomach and intestines. Monitor your pet closely at home for vomiting, dark tarry stools, or signs of abdominal pain over the next 4 to 6 weeks, as strictures (scar tissue blockages) can sometimes develop.
Deferoxamine Mesylate對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。