Clonidine
別名: Duraclon, Catapres, Jenloga, Catapres-TTS
**Purpose:** Your veterinarian has prescribed clonidine to help manage your pet's condition, which may include severe diarrhea, pain management, or off-label use for severe anxiety and phobias. * **Strict Dosing:** Clonidine has a **narrow margin of safety**. Give the exact dose prescribed. **Never give more than directed.** * **Side Effects:** Watch for signs of profound lethargy, weakness, pale gums, or unexpected behavioral changes (such as aggression). Contact your veterinarian if these occur. * **Do Not Stop Abruptly:** Do not suddenly discontinue this medication without consulting your veterinarian, as it can cause a dangerous spike in blood pressure (rebound hypertension). * **Accidental Ingestion:** Keep out of reach of all pets and children. If an overdose occurs, seek emergency veterinary care immediately.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Adjunctive antidiarrheal therapy for refractory cases of inflammatory bowel disease
- Epidural analgesia/analgesia
- Diagnosing hyposomatotropism
- Adjunctive antidiarrheal therapy for refractory cases of inflammatory bowel disease
- Control panic-like responses and fear-based behavioural problems
- Diagnostic test for pituitary dwarfism (hyposomatotropism)
給藥方式
可能的副作用
- Transient hyperglycemia
- Dry mouth
- Constipation
- Sedation
- Aggressive behavior
- Hypotension
- Collapse
- Bradycardia
- Transient sedation
- Rebound hypertension (if withdrawn abruptly)
注意事項與禁忌
- Known hypersensitivity to clonidine
- Severe cardiovascular disease (use with extreme caution)
- Renal disease (use with extreme caution)
- Clonidine has a **narrow margin of safety**. It should be used with caution in patients with severe cardiovascular disease, including conduction disturbances or heart failure. Use very cautiously in patients with renal failure. Abrupt withdrawal, especially when used with beta-blockers, may cause rebound hypertension.
藥物相互作用
- Antihypertensive drugs: Possible additive hypotensive effects
- Beta-adrenergic blocking agents (e.g., propranolol): May enhance bradycardia. If discontinuing, beta-blocker should be stopped first, then clonidine tapered to avoid rebound hypertension.
- CNS depressant drugs (opiates, barbiturates): May exacerbate the actions of other CNS depressant drugs
- Digoxin: Possible additive bradycardia
- Prazosin: May decrease the antihypertensive effects of clonidine
- Tricyclic antidepressants (e.g., amitriptyline): May block the antihypertensive effects of clonidine
- Barbiturates: Increased central nervous system depression and hypotension
- Opiates: Additive sedation, bradycardia, and respiratory depression
- Beta-blockers: Additive hypotensive and bradycardic effects; may exacerbate rebound hypertension upon withdrawal
- Hypotensive agents: Additive lowering of blood pressure
常見問題
Clonidine用於寵物有甚麼用途？
**Purpose:** Your veterinarian has prescribed clonidine to help manage your pet's condition, which may include severe diarrhea, pain management, or off-label use for severe anxiety and phobias. * **Strict Dosing:** Clonidine has a **narrow margin of safety**. Give the exact dose prescribed. **Never give more than directed.** * **Side Effects:** Watch for signs of profound lethargy, weakness, pale gums, or unexpected behavioral changes (such as aggression). Contact your veterinarian if these occur. * **Do Not Stop Abruptly:** Do not suddenly discontinue this medication without consulting your veterinarian, as it can cause a dangerous spike in blood pressure (rebound hypertension). * **Accidental Ingestion:** Keep out of reach of all pets and children. If an overdose occurs, seek emergency veterinary care immediately.
Clonidine對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。