Carbimazole
別名: Vidalta, Neo-Carbimazole, Carbazole, Basolest, Camazol, Carbistad, Cazole, Neo Tomizol, NeoMercazole, Neo-Thyreostat, Thyrostat, Tyrazol, Neo-morphazole, Neo-Mercazole
* **Purpose**: This medication manages your cat's overactive thyroid gland (hyperthyroidism) by reducing the production of thyroid hormones. It is a management tool, not a cure. * **Patience is Key**: It typically takes 1 to 3 weeks to see significant improvement in your cat's symptoms. * **Administration**: Give exactly as prescribed. Do not crush or break sustained-release tablets (like Vidalta). * **Side Effects to Watch For**: Contact your veterinarian if your cat experiences vomiting, loss of appetite, lethargy, or severe facial scratching/itching. * **Safety**: Pregnant women or nursing mothers should handle this medication with caution (wear gloves), as it can cross the placenta and enter breast milk.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Hyperthyroidism
- Hyperthyroidism
- Hyperthyroidism
- Hyperthyroidism
- Hyperthyroidism (Sustained-release tablets)
- Hyperthyroidism
給藥方式
可能的副作用
- Vomiting
- Anorexia
- Depression
- Eosinophilia (usually transient)
- Leukopenia (usually transient)
- Lymphocytosis (usually transient)
- Self-induced excoriations (rare but serious)
- Bleeding (rare but serious)
- Hepatopathy (rare but serious)
- Thrombocytopenia (rare but serious)
- Agranulocytosis (rare but serious)
- Positive direct antiglobulin test (rare but serious)
- Acquired myasthenia gravis (rare but serious)
- Positive ANA (with chronic use)
注意事項與禁忌
- Hypersensitivity to carbimazole or methimazole
- Not recommended in cats intolerant to methimazole
- History of or concurrent hematologic abnormalities
- Liver disease
- Autoimmune disease
- **Hypersensitivity**: Contraindicated in patients hypersensitive to carbimazole or methimazole. **Cross-Reactivity**: Because carbimazole is a prodrug converted into methimazole, cats who have had prior serious reactions to methimazole should receive carbimazole with great caution. **Pregnancy/Nursing**: High levels of methimazole cross the placenta and may induce hypothyroidism in kittens. Levels higher than those found in plasma are found in breast milk. Kittens should be placed on a milk replacer after receiving colostrum from mothers on methimazole. FDA categorizes methimazole as category D for use during pregnancy.
藥物相互作用
- Bupropion: Potential for increased risk for hepatotoxicity; increased monitoring (LFT's) necessary
- Digoxin: Carbimazole may decrease digoxin efficacy
- Warfarin: Potential for decreased anticoagulant efficacy if carbimazole added
- Iodine-131 (Radioiodine): Carbimazole interferes with the uptake and efficacy of radioiodine therapy. It must be discontinued prior to treatment.
- Low iodine prescription diets: Concurrent use is not recommended as it may interfere with the dietary management of hyperthyroidism.
常見問題
Carbimazole用於寵物有甚麼用途？
* **Purpose**: This medication manages your cat's overactive thyroid gland (hyperthyroidism) by reducing the production of thyroid hormones. It is a management tool, not a cure. * **Patience is Key**: It typically takes 1 to 3 weeks to see significant improvement in your cat's symptoms. * **Administration**: Give exactly as prescribed. Do not crush or break sustained-release tablets (like Vidalta). * **Side Effects to Watch For**: Contact your veterinarian if your cat experiences vomiting, loss of appetite, lethargy, or severe facial scratching/itching. * **Safety**: Pregnant women or nursing mothers should handle this medication with caution (wear gloves), as it can cross the placenta and enter breast milk.
Carbimazole對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。