阿曲庫銨
別名: Tracrium, Abbottracurium, Atracur, Faulcurium, Ifacur, Laurak, Mycurium, Relatrac, Sitrac, Trablok, Tracur
藥物類別: Nondepolarizing Neuromuscular Blocker
本藥物是一種高度專業的肌肉鬆弛劑，僅由獸醫專業人員在全身麻醉或重症加護機械通氣期間使用。 * 它能確保您的寵物在精細手術（如眼科手術）期間保持完全靜止，或在病危時幫助牠們配合呼吸機呼吸。 * 因為它僅能放鬆肌肉，並不提供止痛或睡眠效果，所以**總是**會與強效止痛藥和鎮靜劑或麻醉劑一起給予，以確保您的寵物完全失去意識且感到舒適。
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
Veterinary professional? See the full dosing-by-species reference on VetSheet →
用途
- Induction dose
- Intraoperative dose
- Induction of respiratory muscle paralysis during mechanical ventilation
- Critically ill patients when low concentrations of, or no inhalant anesthesia can be used
- Intraoperative dose
- Paralysis for periophthalmic surgery (Rabbits)
- Critically ill patients when low concentrations of, or no inhalant anesthesia can be used
- Neuromuscular blockade augmentation during corneal surgery
- Muscle relaxant to facilitate intubation in patients with severe blunt trauma
- Induction of respiratory muscle paralysis during mechanical ventilation
給藥方式
IV
可能的副作用
- Allergic reactions
- Inadequate or prolonged neuromuscular block
- Hypotension
- Vasodilation
- Bradycardia
- Tachycardia
- Dyspnea
- Bronchospasm
- Laryngospasm
- Rash
- Urticaria
- Injection site reaction
注意事項與禁忌
- Hypersensitivity to atracurium
- Relative contraindication: Myasthenia gravis
- Lack of ventilatory support (must have mechanical ventilation available)
- > **CRITICAL WARNING:** Atracurium has **NO analgesic or sedative/anesthetic actions**. Patients must be appropriately sedated/anesthetized and provided with analgesia. * **Ventilation:** Positive pressure ventilation (preferably mechanical) is absolutely required when using this drug. * **Histamine Release:** May rarely cause significant histamine release; use with caution in patients where this would be hazardous (e.g., severe cardiovascular disease, asthma). * **Myasthenia Gravis:** Use with extreme caution, or not at all, in patients suffering from myasthenia gravis. * **Vagal Tone:** Has minimal cardiac effects and will not counteract bradycardia or vagal stimulation induced by other anesthetic agents.
藥物相互作用
- Aminoglycoside antibiotics (e.g., gentamicin): May enhance the neuromuscular blocking activity of atracurium
- General anesthetics (enflurane, isoflurane, halothane, sevoflurane): May enhance and prolong the neuromuscular blocking activity
- Bacitracin, Polymyxin B (systemic): May enhance neuromuscular blocking activity
- Procainamide: May enhance neuromuscular blocking activity
- Quinidine: May enhance neuromuscular blocking activity
- Lithium: May enhance neuromuscular blocking activity
- Magnesium salts: May enhance neuromuscular blocking activity
- Anticonvulsants (Phenytoin, Carbamazepine): Reported to decrease both the effects and duration of neuromuscular blockade
- Other muscle relaxant drugs: May cause a synergistic or antagonistic effect
- Succinylcholine: May speed the onset of action and enhance the neuromuscular blocking actions of atracurium. Do not give atracurium until succinylcholine effects have diminished.
常見問題
阿曲庫銨用於寵物有甚麼用途？
本藥物是一種高度專業的肌肉鬆弛劑，僅由獸醫專業人員在全身麻醉或重症加護機械通氣期間使用。 • 它能確保您的寵物在精細手術（如眼科手術）期間保持完全靜止，或在病危時幫助牠們配合呼吸機呼吸。 • 因為它僅能放鬆肌肉，並不提供止痛或睡眠效果，所以總是會與強效止痛藥和鎮靜劑或麻醉劑一起給予，以確保您的寵物完全失去意識且感到舒適。
阿曲庫銨對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。