Amantadine HCl
別名: Symmetrel, Adekin, Amanta, Amantagamma, Amantan, Amantrel, Amixx, Antadine, Antiflu-DES, Atarin, Atenegine, Cerebramed, Endantadine, Infectoflu, Influ-A, Lysovir, Mantadine, Mantadix, Mantidan, Padiken, Symadine, Viroifral, Virucid
* **Patience is Key**: When used for chronic pain, this medication must be given consistently as prescribed. It may take a week or more to see noticeable improvements in your pet's comfort. * **Side Effects**: Mild gastrointestinal effects (loose stools, gas, diarrhea) or mild agitation/restlessness may occur, especially during the first few days of treatment. Contact your veterinarian if these signs become severe or persist. * **Taste**: If using the liquid formulation, be aware that it has a very bitter taste. Your veterinarian or a compounding pharmacy may be able to provide a flavored version. * **Safety Warning**: Overdoses can be life-threatening. Keep this medication strictly out of reach of children and all pets.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Osteoarthritis pain when NSAIDs alone are not effective
- Adjunctive therapy for chronic pain
- To decrease wind-up
- Analgesia (adjunct for chronic pain)
- Adjunctive therapy for chronic pain
- Adjunctive therapy for chronic pain
- Adjunctive therapy for chronic pain
- Analgesia (adjunct for chronic pain)
- Acute treatment of equine-2 influenza
給藥方式
可能的副作用
- Agitation or restlessness (especially early in therapy)
- Loose stools, flatulence, or diarrhea
- Narrow safety margin in cats (potential for neurotoxicity)
- Seizures (reported in horses given IV)
注意事項與禁忌
- Known hypersensitivity to amantadine or rimantadine
- Untreated angle-closure glaucoma
- Extra-label use in chickens, turkeys, and ducks (Prohibited by FDA)
- Use with caution in patients with **liver disease, renal disease** (dosage adjustment may be required as it is primarily renally excreted), **congestive heart failure, active psychoses, eczematoid dermatitis, or seizure disorders**. > **Warning**: The FDA strictly prohibits the extra-label use of amantadine and other influenza antivirals in poultry (chickens, turkeys, ducks).
藥物相互作用
- Anticholinergic drugs: May enhance the anticholinergic effects of amantadine.
- CNS Stimulants (e.g., selegiline): Concomitant use may increase the CNS stimulatory effects of amantadine.
- Trimethoprim/sulfa, quinidine, quinine, thiazide diuretics, triamterene: May decrease the renal excretion of amantadine, yielding higher and potentially toxic blood levels.
- Urinary acidifiers (e.g., methionine, ammonium chloride, ascorbic acid): May increase the renal excretion of amantadine, potentially decreasing its efficacy.
- Trimethoprim/Sulfamethoxazole: Decreased renal clearance of amantadine, potentially leading to toxicity
- Anticholinergics: Increased anticholinergic side effects (e.g., dry mouth, urine retention)
- CNS stimulants: Increased risk of agitation, restlessness, or seizures
常見問題
Amantadine HCl用於寵物有甚麼用途？
* **Patience is Key**: When used for chronic pain, this medication must be given consistently as prescribed. It may take a week or more to see noticeable improvements in your pet's comfort. * **Side Effects**: Mild gastrointestinal effects (loose stools, gas, diarrhea) or mild agitation/restlessness may occur, especially during the first few days of treatment. Contact your veterinarian if these signs become severe or persist. * **Taste**: If using the liquid formulation, be aware that it has a very bitter taste. Your veterinarian or a compounding pharmacy may be able to provide a flavored version. * **Safety Warning**: Overdoses can be life-threatening. Keep this medication strictly out of reach of children and all pets.
Amantadine HCl對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。