Acarbose
別名: Precose, Glucobay, Prandase, Glucor, Glumida
Acarbose helps control your pet's blood sugar by slowing down the digestion of carbohydrates in their food. * **Timing is crucial:** Give this medication **right before feeding** for the best results. It will not work well if your pet grazes on food throughout the day. * **Side Effects:** Diarrhea and/or excessive gas are the most likely side effects. Contact your veterinarian if these become serious or do not resolve. * **Low Blood Sugar (Hypoglycemia):** Acarbose alone does not cause low blood sugar, but it can increase the risk if your pet is also receiving insulin. Watch closely for signs of low blood sugar: **seizures (convulsions), collapse, rear leg weakness or paralysis, muscle twitching, unsteadiness, tiredness, or depression**. If these occur, call your veterinarian immediately. * **Emergency Sugar:** If your pet experiences low blood sugar and you need to give sugar by mouth, use **corn syrup or pure glucose** (like Karo syrup). Do NOT use regular table sugar (sucrose), as this medication stops table sugar from being absorbed. * **Patience:** It may take up to two weeks for the drug to reach its peak effect in controlling blood sugar.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Improve glycemic control and reduce insulin dependence
- Reduce insulin dosage and thereby reduce hypoglycemia occurrence
- Adjunctive glycemic control
- For dogs poorly controlled with insulin and dietary therapy when another reason for the poor control cannot be identified
- Adjunctive glycemic control
給藥方式
可能的副作用
- Flatulence
- Soft stools
- Diarrhea (dose-dependent)
- Weight loss (reported in dogs)
- May contribute to hypoglycemia if used concurrently with other hypoglycemic agents (e.g., insulin)
注意事項與禁忌
- Underweight animals (may have deleterious effects on nutritional status)
- Known hypersensitivity to acarbose
- Diabetic ketoacidosis
- Inflammatory bowel disease
- Colonic ulceration
- Partial intestinal obstruction or predisposition to obstruction
- Chronic intestinal disease with marked disorders of digestion or absorption
- Conditions where excessive gas formation would be detrimental
- > **Important Precautions:** * **Hepatic/Renal Impairment:** Use with caution in patients with renal dysfunction or severe liver disease. Patients with severe renal dysfunction may attain serum levels approximately 5 times those of normal subjects. * **Pregnancy:** Safety in pregnancy has not been established (FDA Category B in humans). Weigh potential risks versus benefits. * **Hypoglycemia Risk:** While acarbose alone does not cause hypoglycemia, it can exacerbate it when used with insulin. If oral treatment for hypoglycemia is needed, **use pure glucose (dextrose), NOT sucrose**, as acarbose blocks the breakdown of sucrose.
藥物相互作用
- Charcoal: Intestinal adsorbents may reduce the efficacy of acarbose.
- Digoxin: Acarbose may reduce digoxin blood concentrations.
- Hyperglycemic Agents (corticosteroids, thiazides, estrogens, phenothiazines, thyroid hormones, calcium channel blockers): May negate the antihyperglycemic effects of acarbose.
- Pancreatin, Pancrelipase, or Amylase: Exogenous enzyme formulations may reduce the efficacy of acarbose.
常見問題
Acarbose用於寵物有甚麼用途？
Acarbose helps control your pet's blood sugar by slowing down the digestion of carbohydrates in their food. * **Timing is crucial:** Give this medication **right before feeding** for the best results. It will not work well if your pet grazes on food throughout the day. * **Side Effects:** Diarrhea and/or excessive gas are the most likely side effects. Contact your veterinarian if these become serious or do not resolve. * **Low Blood Sugar (Hypoglycemia):** Acarbose alone does not cause low blood sugar, but it can increase the risk if your pet is also receiving insulin. Watch closely for signs of low blood sugar: **seizures (convulsions), collapse, rear leg weakness or paralysis, muscle twitching, unsteadiness, tiredness, or depression**. If these occur, call your veterinarian immediately. * **Emergency Sugar:** If your pet experiences low blood sugar and you need to give sugar by mouth, use **corn syrup or pure glucose** (like Karo syrup). Do NOT use regular table sugar (sucrose), as this medication stops table sugar from being absorbed. * **Patience:** It may take up to two weeks for the drug to reach its peak effect in controlling blood sugar.
Acarbose對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。