Grapiprant
Ayrıca bilinen adıyla: Galliprant
Give this medication exactly as prescribed by your veterinarian. It can be given **with or without food**. Watch for side effects such as **vomiting, diarrhea, or loss of appetite**. If these occur, stop the medication and contact your vet. **Do not** give your dog any other pain medications (like aspirin, ibuprofen, or other veterinary NSAIDs) while they are taking grapiprant.
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
Veterinary professional? See the full dosing-by-species reference on VetSheet →
What it is used for
- Management of mild to moderate pain caused by osteoarthritis
How it is given
Possible side effects
- Vomiting
- Diarrhea
- Anorexia
- Lethargy
- Decreased serum albumin
- Soft-formed faeces
- Diarrhoea
- Inappetence
- Mild decreases in serum albumin and total protein
- Haematemesis (very rare)
- Haemorrhagic diarrhoea (very rare)
Cautions & contraindications
- Hypersensitivity to grapiprant
- Concurrent use with other NSAIDs or corticosteroids
- Breeding, pregnant, or lactating dogs
- Dogs under 9 months of age or weighing less than 3.6 kg
- Dogs under 9 months of age
- Dogs weighing less than 3.6 kg
- Cats (not authorized for use)
- Known hypersensitivity to grapiprant
- Use with caution in dogs with pre-existing **hepatic** or **renal** disease, or those with a history of **gastrointestinal** disease. Monitor liver enzymes, kidney values, and clinical signs of GI upset. > **Clinical Pearl:** Although COX-sparing, gastrointestinal adverse effects (vomiting, diarrhea) remain the most commonly reported side effects in clinical practice.
Drug interactions
- Other NSAIDs: Increased risk of gastrointestinal toxicity
- Corticosteroids: Increased risk of gastrointestinal ulceration
- Highly protein-bound drugs: Potential competition for protein binding sites
- Other NSAIDs (e.g., meloxicam, carprofen): Increased risk of gastrointestinal toxicity and adverse effects. Concurrent use should be avoided.
- Corticosteroids (e.g., prednisolone, dexamethasone): Increased risk of gastrointestinal ulceration and adverse effects. Concurrent use should be avoided.
Sık sorulan sorular
What is Grapiprant used for in pets?
Give this medication exactly as prescribed by your veterinarian. It can be given with or without food. Watch for side effects such as vomiting, diarrhea, or loss of appetite. If these occur, stop the medication and contact your vet. Do not give your dog any other pain medications (like aspirin, ibuprofen, or other veterinary NSAIDs) while they are taking grapiprant.
Is Grapiprant safe for my pet?
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
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