Tacrolimus

ชื่ออื่น: Protopic, Prograf, Advagraf

Drug class: Immunosuppressant (Calcineurin inhibitor)

Compiled from veterinary literature and clinical references·How we create this

Wear gloves when applying the ointment to your pet's skin or eyes. Wash hands thoroughly after use. Do not allow other pets to lick the treated area. > **Warning:** If using oral medication, do not switch brands without consulting your veterinarian, as different brands are absorbed differently. Pregnant women should avoid handling this medication if possible.

Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.

Veterinary professional? See the full dosing-by-species reference on VetSheet →

What it is used for

How it is given

TopicalOphthalmicPO

Possible side effects

Topical: local irritation, erythema, pruritus
Ophthalmic: mild ocular irritation
Systemic: GI upset (vomiting, diarrhea), nephrotoxicity, neurotoxicity, secondary infections

Cautions & contraindications

Hypersensitivity to macrolides
Active systemic infections
Malignancy (for systemic use)
> **Warning:** Avoid switching between oral brands due to narrow therapeutic index and variable bioavailability. Wear gloves when applying topical formulations to avoid inadvertent human exposure. Monitor blood levels if used systemically.

Drug interactions

Ketoconazole: Inhibits CYP3A metabolism, significantly increasing systemic tacrolimus levels
Erythromycin: Inhibits metabolism, increasing tacrolimus levels
Grapefruit juice: Increases systemic absorption and blood levels of tacrolimus

คำถามที่พบบ่อย

What is Tacrolimus used for in pets?

Wear gloves when applying the ointment to your pet's skin or eyes. Wash hands thoroughly after use. Do not allow other pets to lick the treated area. > Warning: If using oral medication, do not switch brands without consulting your veterinarian, as different brands are absorbed differently. Pregnant women should avoid handling this medication if possible.

Is Tacrolimus safe for my pet?

Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.

บทความนี้เพื่อการศึกษาทั่วไป ไม่ใช่คำแนะนำทางสัตวแพทย์ หากสัตว์เลี้ยงไม่สบาย โปรดปรึกษาสัตวแพทย์

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