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Pamidronate

Também conhecido como: Aredia

Drug class: Bisphosphonate

Pamidronate is administered as a slow intravenous drip at the veterinary hospital. * It is used to treat dangerously high blood calcium levels or to help relieve pain from bone cancer. * Because it can affect the kidneys and blood salt levels, your veterinarian will likely recommend blood tests before and after treatment to monitor kidney function, calcium, and phosphorus levels. * Let your vet know immediately if your pet experiences vomiting, diarrhea, muscle twitching, or extreme lethargy after treatment.

Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.

Veterinary professional? See the full dosing-by-species reference on VetSheet →

What it is used for

  • Hypercalcaemia / Bone tumour pain
  • Cholecalciferol-induced toxicosis
  • Hypercalcaemia

How it is given

IV

Possible side effects

  • Renal toxicity
  • Nausea
  • Diarrhoea
  • Hypocalcaemia
  • Hypophosphataemia
  • Hypomagnesaemia
  • Hypersensitivity reactions
  • Ophthalmic syndromes (reported in humans)
  • Bone pain (reported in humans)
  • Electrolyte abnormalities (reported in humans)
  • Blood dyscrasias (reported in humans)

Cautions & contraindications

  • Renal dysfunction
  • Normal handling precautions should be observed. **Adequate hydration** is critical. Monitor renal parameters (BUN, creatinine) and serum electrolytes (calcium, phosphorus, magnesium) closely. Administer strictly as a **slow intravenous infusion** (over 2-4 hours) diluted in 0.9% NaCl to minimize nephrotoxicity.

Drug interactions

  • Aminoglycosides: Concurrent use may result in severe hypocalcaemia
  • NSAIDs: Increased risk of renal toxicity; use with caution

Perguntas frequentes

What is Pamidronate used for in pets?

Pamidronate is administered as a slow intravenous drip at the veterinary hospital. * It is used to treat dangerously high blood calcium levels or to help relieve pain from bone cancer. * Because it can affect the kidneys and blood salt levels, your veterinarian will likely recommend blood tests before and after treatment to monitor kidney function, calcium, and phosphorus levels. * Let your vet know immediately if your pet experiences vomiting, diarrhea, muscle twitching, or extreme lethargy after treatment.

Is Pamidronate safe for my pet?

Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.

Este artigo é educação geral e não substitui orientação veterinária. Se o pet estiver mal, consulte um veterinário.

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