틸미코신

용도

• Susceptible infections
• Treatment of pneumonic pasteurellosis
• Susceptible infections
• Susceptible infections (Rabbits) - Regimen 1
• Susceptible infections (Rabbits) - Regimen 2

투여 방법

가능한 부작용

• Local tissue reaction and trim loss (if given IM)
• Edema at the site of subcutaneous injection
• Severe cardiovascular toxicity (fatalities) if given IV
• Fatalities in swine, non-human primates, and potentially horses if injected
• Severe reactions in camelids

주의사항 및 금기

• Intravenous (IV) administration (can be fatal)
• Use in automatically powered syringes
• Injection in swine, non-human primates, horses, and camelids
• Use in lactating ewes if milk is intended for human consumption
• Use in veal calves
• Use in female dairy cattle 20 months or older
• > **HUMAN SAFETY WARNING**: Accidental self-injection can be fatal. Do not use automatically powered syringes. Avoid contact with eyes. * **Species Sensitivity**: Highly toxic when injected in swine, equines, camelids, and primates. * **Pregnancy/Breeding**: Safe use in pregnant animals or animals intended for breeding has not been demonstrated. * **Administration**: Give strictly via subcutaneous injection in approved species. Intramuscular injection causes severe tissue reactions; intravenous injection is often fatal.

약물 상호작용

• Epinephrine: Increased mortality associated with tilmicosin in swine.
• Other Macrolides / Lincosamides: Potential cross-resistance and competitive binding at the 50S ribosomal subunit (extrapolated from erythromycin).

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