숙시머

용도

• Lead poisoning
• Lead poisoning
• Lead poisoning
• Lead poisoning
• Lead poisoning
• Lead poisoning

투여 방법

가능한 부작용

• Gastrointestinal upset (vomiting, diarrhea)
• Flu-like symptoms (fatigue, body aches)
• Increased liver enzymes (AST, ALT)
• Rash
• Unpleasant sulfurous odor imparted to breath, saliva, urine, and feces

주의사항 및 금기

• Hypersensitivity to succimer
• Continued exposure to the lead source (source must be removed prior to or concurrently with therapy)
• ### Important Precautions * **Source Removal:** Chelation therapy should *only* be attempted if the source of lead (e.g., lead paint, sinkers, shot) is removed from the GI tract and environment to prevent further absorption. * **Laboratory Interferences:** * Can cause **false-positive urine ketones** when using nitroprusside reagents (e.g., Ketostix). * Can cause falsely low measurements of CPK or serum uric acid. * **Pregnancy & Nursing:** FDA Category C. Fetotoxic and teratogenic at high doses in mice. Safety in pregnant or nursing animals is unknown; use with extreme caution and discourage nursing.

약물 상호작용

• Other chelating agents (CaEDTA, dimercaprol, trientine, penicillamine): Concomitant use is not recommended in humans due to potential for increased toxicity or altered efficacy.

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