소마토트로핀 / 성장 호르몬

용도

• Growth hormone replacement
• Growth hormone replacement

투여 방법

가능한 부작용

• Hyperglycemia
• Insulin resistance / Diabetes mellitus
• Acromegaly (with prolonged use)
• Antibody formation (when using human GH in pets)
• Injection site reactions
• Diabetogenic effect (hyperglycemia/diabetes mellitus)
• Local injection site reactions
• Antibody formation (reducing long-term efficacy)

주의사항 및 금기

• Closed epiphyseal plates (if seeking linear growth)
• Neoplasia (may stimulate tumor growth)
• Diabetes mellitus
• Hypersensitivity to the drug or formulation components
• Patients with closed epiphyses (unless treating specific adult-onset deficiencies)
• Known hypersensitivity
• Active neoplasia
• > **Important:** Monitor blood glucose closely, as somatotropin is highly diabetogenic. Use with extreme caution in patients with a history of pancreatitis or those at risk for diabetes mellitus. In small animals, monitor for signs of **acromegaly** (broadening of facial features, increased interdental spaces, organomegaly) during prolonged therapy. GH therapy can also unmask underlying hypothyroidism.

약물 상호작용

• Glucocorticoids: May antagonize the growth-promoting effects of somatotropin.
• Insulin: Somatotropin induces insulin resistance, potentially requiring significant adjustments in insulin dosage for diabetic patients.

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