퀴나크린

용도

• Giardia
• Coccidiosis
• Giardia
• Coccidiosis
• Giardia or other susceptible protozoa (second-choice)
• Giardia or other susceptible protozoa (second-choice)
• Hemoprotozoal infections

투여 방법

가능한 부작용

• Yellowing of skin and urine (benign)
• Anorexia
• Nausea and vomiting
• Diarrhea
• Abnormal behaviors ('fly biting', agitation)
• Lethargy
• Pruritus
• Fever
• Hypersensitivity reactions (rare)
• Hepatopathy (rare)
• Aplastic anemia (rare)
• Corneal edema (rare)
• Retinopathy (rare)

주의사항 및 금기

• Hepatic dysfunction (relative)
• Pregnancy (relative, potential teratogen)
• Psychotic disorders (in humans)
• Psoriasis (in humans)
• Porphyria (in humans)
• > **Hepatic Impairment**: Use with extreme caution in patients with hepatic dysfunction, as the drug concentrates heavily in the liver. > **Pregnancy**: FDA Category C. Has caused fetal death in rats at high doses and is implicated in human birth defects. Weigh risks vs. benefits. > **Laboratory Interference**: Can cause falsely elevated plasma and urine cortisol values due to interfering fluorescence.

약물 상호작용

• Alcohol: May cause a 'disulfiram-like' reaction if used concurrently.
• Hepatotoxic Drugs: Quinacrine concentrates in the liver; use with caution with other hepatotoxic agents.
• Primaquine: Quinacrine increases the toxicity of primaquine; do not use simultaneously.

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