이미다프릴

용도

• Congestive heart failure, proteinuria, or hypertension
• Cardiac disease or proteinuria

투여 방법

가능한 부작용

• Hypotension
• Hyperkalemia
• Azotemia
• Anorexia (rare)
• Vomiting (rare)
• Diarrhea (rare)

주의사항 및 금기

• Acute renal failure
• Congenital heart disease
• Hemodynamically relevant stenoses (e.g., aortic stenosis)
• Obstructive hypertrophic cardiomyopathy
• Hypovolemia
• Breeding, pregnant, or lactating bitches
• Dogs weighing < 4 kg (safety not established)
• Regular monitoring of **blood pressure**, **serum creatinine**, **urea**, and **electrolytes** is strongly recommended during ACE inhibitor treatment. Dosage should be reduced if there are clinical signs of hypotension (e.g., weakness, disorientation). Use cautiously in patients with hyponatremia or outflow tract obstructions.

약물 상호작용

• Spironolactone: Could result in hyperkalemia, though in practice, spironolactone and ACE inhibitors appear safe to use concurrently.
• Potassium supplements: Increased risk of hyperkalemia.
• NSAIDs: Increased risk of nephrotoxicity and decreased clinical efficacy of the ACE inhibitor.
• Diuretics: Increased risk of hypotension.
• Vasodilators (e.g., anesthetic agents, antihypertensives): Increased risk of hypotension.
• Beta-blockers: Increased risk of hypotension when combined with negative inotropes.

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