세픽심

용도

• Susceptible infections
• Infectious endocarditis
• UTI
• Respiratory, systemic infections
• Susceptible infections

투여 방법

가능한 부작용

• Gastrointestinal distress (vomiting, diarrhea)
• Hypersensitivity reactions (urticaria, pruritus, fever)

주의사항 및 금기

• Hypersensitivity to cefixime or other cephalosporins
• > **Important Precautions:** * **Renal Impairment:** Because cefixime is primarily excreted by the kidneys, dosages and/or dosage frequency may need to be adjusted in patients with significantly diminished renal function. * **Cross-Reactivity:** Use with caution in patients allergic to penicillins due to the potential for cross-reactivity. * **Neurologic Conditions:** Use with caution in patients with seizure disorders, as high levels of beta-lactams can lower the seizure threshold. * **Laboratory Interference:** May cause false-positive urine glucose determinations when using cupric sulfate solution (e.g., Clinitest) and false-positive urinary ketones with nitroprusside tests.

약물 상호작용

• Probenecid: Competitively blocks the tubular secretion of most cephalosporins, thereby increasing serum levels and serum half-lives.
• Salicylates: May displace cefixime from plasma protein binding sites; clinical significance is unclear.

자주 묻는 질문