세페핌

용도

• For susceptible infections in foals (gram-negative infections)
• Neonates with poor aminoglycoside kinetics or documented multi-resistant infections
• For susceptible infections

투여 방법

가능한 부작용

• Loose stools or diarrhea
• Pain on IM injection
• Injection site inflammation
• Hypersensitivity reactions (rash, anaphylaxis)
• Neurologic effects (encephalopathy, seizures) in patients with renal dysfunction

주의사항 및 금기

• Hypersensitivity to cefepime or other cephalosporins
• Caution in patients with severe renal impairment (dosage adjustment required)
• Dosage adjustment is recommended in patients with severe renal impairment to prevent neurotoxicity. May cause false-positive urine glucose determinations when using the copper reduction method (e.g., Clinitest). May cause a false-positive direct Coombs' test, particularly in azotemic patients. IM injections can be painful; 1% lidocaine may be used as a diluent to alleviate pain.

약물 상호작용

• Aminoglycosides: Potential for increased risk of nephrotoxicity; monitor renal function closely.

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