スフェンタニル

使用用途

• Acute pain relief in an emergency
• As a pre-med
• For epidural analgesia
• Acute pain relief in an emergency
• For surgical pain

投与方法

考えられる副作用

• Respiratory depression (dose-related)
• CNS depression
• Bradycardia
• Skeletal muscle rigidity
• Asystole (rare)
• Hypercarbia (rare)
• Hypersensitivity reactions (rare)

注意事項と禁忌

• Hypersensitivity to sufentanil or other opioids
• > **Warning:** Sufentanil is a Class-II controlled substance with extreme potency. It should only be used in situations where patient vital signs can be continuously monitored. * **Geriatric/Debilitated Patients:** Use with caution; initial dosage reduction may be required, particularly in those with diminished cardiopulmonary function. * **Organ Impairment:** Use with caution in patients with severely diminished renal or hepatic function. * **Pregnancy:** Avoid systemic administration to mothers close to giving birth, as offspring may show behavioral alterations (hypotonia, depression).

薬物相互作用

• Beta-adrenergic blockers: May increase bradycardia and hypotension
• Calcium-channel blockers: May increase bradycardia and hypotension
• CNS depressants (e.g., barbiturates): Additive effects can occur, exacerbating CNS or respiratory depression
• Nitrous oxide: Can cause cardiovascular depression if used with high dose sufentanil

よくある質問