プロリゲストン

使用用途

• Suppression of oestrus
• Permanent postponement of oestrus
• Acromegaly
• Postponement of oestrus / Miliary dermatitis

投与方法

考えられる副作用

• Unpredictable duration of anoestrus (up to 3 years in some bitches)
• Temperament changes (listlessness and depression)
• Polyuria and polydipsia (increased thirst)
• Polyphagia (increased appetite)
• Cystic endometrial hyperplasia / Pyometra
• Diabetes mellitus
• Acromegaly
• Adrenocortical suppression
• Mammary enlargement, lactation, or neoplasia
• Injection site irritation
• Coat colour changes at the injection site
• Calcinosis circumscripta at the injection site

注意事項と禁忌

• Diabetic animals (insulin requirements are likely to change unpredictably)
• Bitches before or at their first oestrus
• As coat colour changes may occasionally occur, injection into the medial side of the flank fold is recommended for thin-skinned or show animals. **Clinical Pearl**: While proligestone does not appear to be associated with as many or as serious adverse effects as older progestogens (e.g., megestrol acetate, medroxyprogesterone acetate), owners must still be thoroughly counseled on the risks of pyometra and diabetes mellitus.

よくある質問