オキシトシン
別称: Pitocin, Syntocinon
薬の分類: Hormonal Agent
オキシトシンは、ペットの分娩を助けたり、乳汁分泌を促すために使用される強力なホルモンです。 * **専門家による監視が必要：** その効果を適切に監視できる獣医師の直接の指導または投与の下でのみ使用すべきです。 * **誤用のリスク：** 胎児が引っかかっている場合や産道が完全に開いていない状態でオキシトシンを投与すると、子宮破裂や胎児の死亡など、深刻な合併症を引き起こす可能性があります。 * **点鼻スプレー：** 乳汁分泌を促すために点鼻スプレーが処方された場合は、指示通りに（通常は授乳の5〜10分前に）投与してください。
用量はペットの状態に応じて獣医師が決定します。獣医師の指導なしに人用医薬品や他のペットの処方薬を与えないでください。
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使用用途
- For retained placenta in patients with uterine atony
- For mild to moderate cases of acute post-partum metritis
- For retained placenta in patients with uterine atony
- For mild to moderate cases of acute post-partum metritis
- To control post-extraction cervical and uterine bleeding after internal manipulations
- To promote uterine involution after uterine prolapse manual reduction
- To treat primary uterine inertia
- For adjunctive treatment of metritis
- To induce milk let-down (secondary agalactia)
- For retained placenta
- To reduce incidence of retained placenta
- For mild to moderate cases of acute post-partum metritis
- To augment uterine contractions during parturition
- For obstetrical use in cows
- For milk let-down in cows
- To augment or initiate uterine contractions during parturition in properly evaluated mares
- To prevent luteolysis (prolong corpus luteum lifespan)
- For evacuation of uterine fluid
- To aid in removal of retained fetal membranes
- To aid in removal of retained fetal membranes (alternative)
- For mild to moderate cases of acute post-partum metritis
- To treat esophageal obstruction ('choke')
- As a uterotonic agent
- For egg expulsion
- For adjunctive treatment of agalactia syndrome (MMA) in sows
- For adjunctive treatment of agalactia syndrome (MMA) in sows (alternative)
- For retained placenta in patients with uterine atony
- To augment uterine contractions during parturition
- For obstetrical use in sows
- For mild to moderate cases of acute post-partum metritis
- For mild to moderate cases of acute post-partum metritis (alternative)
- For milk let-down in sows
- Uterotonic / Obstetrical use (Mice, Rats, Gerbils, Hamsters, Guinea pigs, Chinchillas)
- To augment uterine contractions during parturition
- For uterine inertia (if no fetuses in birth canal, cervix dilated, obstruction ruled out)
- For uterine inertia (mini-dose protocol)
- To induce milk let-down (adequate milk production, tolerates nursing)
- For secondary agalactia
- For adjunctive treatment of acute metritis
- To promote uterine involution after uterine prolapse manual reduction
- For egg binding
- To induce oviposition
投与方法
IMIVSCIntranasal
考えられる副作用
- Uterine cramping and discomfort
- Tetanic uterine contractions (at high doses)
- Uterine rupture
- Fetal compromise or death (due to placental compression)
- Water intoxication (with prolonged high-dose infusions)
- Hypersensitivity reactions (more common with non-synthetic products)
注意事項と禁忌
- Dystocia due to abnormal fetal presentation (unless corrected)
- Closed or unrelaxed cervix
- Known hypersensitivity to oxytocin
- Significant cephalopelvic disproportion
- Obstetrical emergencies where surgical intervention (C-section) is warranted
- Pregnancy (for nasally administered oxytocin)
- > **Critical Warning:** Always evaluate the patient for obstructive dystocia and ensure the cervix is dilated before administration. * **Metabolic Status:** Treat hypoglycemia or hypocalcemia before using oxytocin, as uterine fatigue is often secondary to these metabolic deficits. * **Water Intoxication:** While oxytocin has minimal antidiuretic properties, water intoxication can occur if administered at too rapid a rate or if excessively large volumes of electrolyte-free IV fluids are given concurrently. Signs include depression, coma, and seizures. * **Fetal Monitoring:** Monitor fetal heart rates if possible, as excessive uterine contractions can cause fetal hypoxia.
薬物相互作用
- Thiopental: May delay thiopental anesthesia (reported in humans; clinical significance in animals is not firmly established).
- Vasoconstrictors (Sympathomimetics): Concurrent use post-partum may result in severe hypertension. Monitor closely.
よくある質問
オキシトシンはペットにどう使われていますか？
オキシトシンは、ペットの分娩を助けたり、乳汁分泌を促すために使用される強力なホルモンです。 • 専門家による監視が必要： その効果を適切に監視できる獣医師の直接の指導または投与の下でのみ使用すべきです。 • 誤用のリスク： 胎児が引っかかっている場合や産道が完全に開いていない状態でオキシトシンを投与すると、子宮破裂や胎児の死亡など、深刻な合併症を引き起こす可能性があります。 • 点鼻スプレー： 乳汁分泌を促すために点鼻スプレーが処方された場合は、指示通りに（通常は授乳の5〜10分前に）投与してください。
オキシトシンはうちのペットに安全ですか？
用量はペットの状態に応じて獣医師が決定します。獣医師の指導なしに人用医薬品や他のペットの処方薬を与えないでください。
この記事は一般的な健康教育を目的としており、専門的な獣医学的アドバイスの代わりにはなりません。ペットが調子悪い場合は、獣医師にご相談ください。