イバフロキサシン

使用用途

• Susceptible infections (dermal infections: soft tissue infections-wounds, abscesses; upper respiratory tract infections)
• Susceptible infections (dermal infections: superficial and deep pyoderma, wounds, abscesses)

投与方法

考えられる副作用

• Diarrhea
• Soft feces
• Vomiting
• Dullness
• Anorexia
• Salivation
• Elevated hepatic enzymes (rare, class effect)
• Ataxia (rare, class effect)
• Seizures (rare, class effect)
• Depression/Lethargy (rare, class effect)
• Nervousness (rare, class effect)

注意事項と禁忌

• Dogs less than 8 months of age
• Giant breed dogs less than 18 months of age
• Cats less than 8 months of age
• Known quinolone hypersensitivity
• Use should be based upon susceptibility testing. Safety has not been established in pregnant cats or in lactating dogs and cats, though the UK label states it can be used during pregnancy in dogs. Use with caution in patients with central nervous system disorders.

薬物相互作用

• NSAIDs: Should not be used with NSAIDs in dogs with a history of seizures due to increased risk of CNS stimulation.
• Antacids or Supplements (iron, zinc, magnesium, aluminum, calcium): Cations may bind to ibafloxacin and prevent its gastrointestinal absorption.
• Cyclosporine: Fluoroquinolones may exacerbate the nephrotoxicity of systemic cyclosporine.
• Nitrofurantoin: May antagonize the antimicrobial activity of fluoroquinolones; concomitant use is not recommended.
• Quinidine: Increased risk for cardiotoxicity.
• Sucralfate: May inhibit absorption of ibafloxacin; separate doses by at least 2 hours.
• Theophylline: Ibafloxacin may increase theophylline blood levels.

よくある質問