セファクロル

使用用途

• Skin or soft tissue infections
• Systemic, lower respiratory tract infections
• Skin or soft tissue infections
• Systemic, lower respiratory tract infections

投与方法

考えられる副作用

• Nausea
• Diarrhea
• Hypersensitivity reactions (including anaphylaxis)
• Serum-sickness-like reactions
• Erythema multiforme (rare)
• Rash
• Transient increases in liver enzymes
• Transient increases in BUN and serum creatinine

注意事項と禁忌

• Known hypersensitivity to cephalosporins
• Use with caution in patients with documented penicillin allergy (potential cross-reactivity)
• Severe renal impairment (requires dosage adjustment)
• Use cautiously in patients with documented penicillin allergies due to the potential for cross-reactivity. Dosage adjustment is recommended in patients with severe renal impairment. Cephalosporins may cause false-positive urine glucose determinations when using the copper reduction method and falsely elevated serum or urine creatinine values when using the Jaffe reaction. May cause a false-positive direct Coombs' test.

薬物相互作用

• Antacids (magnesium or aluminum-containing): Reduces extent of absorption of extended-release cefaclor tablets
• Probenecid: Reduced renal excretion of cefaclor
• Warfarin: Rare reports of increased anticoagulant effect

よくある質問