Pergolide
Također poznato kao: Permax, Celance, Nopar, Parkotil, Parlide, Pharken
> **Important:** Pergolide manages Equine Cushing's Disease (PPID) but does not cure it. Treatment is typically required for the rest of the horse's life. * **Patience is Key:** It may take several weeks to months to see noticeable improvements in your horse's hair coat, energy levels, and weight. * **Appetite Changes:** Some horses may eat less during the first week of treatment. If this happens, contact your veterinarian; a temporary dose reduction usually resolves the issue. * **Storage Matters:** If using a compounded liquid suspension, keep it in the refrigerator, protected from light. **Discard it after 30 days or if it changes color**, as the medication degrades quickly in water. * **Holistic Care:** Proper nutrition, regular farrier care, and weight management are crucial alongside medication for the successful treatment of this disease.
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
Veterinary professional? See the full dosing-by-species reference on VetSheet →
What it is used for
- Equine 'Cushing's-like' Disease [pituitary pars intermedia dysfunction (PPID)]
- Equine 'Cushing's-like' Disease [pituitary pars intermedia dysfunction (PPID)]
- Equine 'Cushing's-like' Disease [pituitary pars intermedia dysfunction (PPID)]
How it is given
Possible side effects
- Anorexia/decreased appetite (up to 10% of horses during the first week)
- Colic (rare)
- Diarrhea (rare)
- Lethargy (dogs)
- Vomiting (dogs)
- Hypertension (dogs)
- Ptosis (dogs)
Cautions & contraindications
- Hypersensitivity to pergolide or other ergot derivatives
- Safety in pregnant horses has not been established. May interfere with lactation due to its ergot-derivative nature. Compounded aqueous suspensions are highly unstable; they must be stored in dark containers, refrigerated, and discarded after 30 days or if any color change occurs.
Drug interactions
- Dopamine antagonists (e.g., phenothiazines): May decrease the effects of pergolide
- Metoclopramide: May decrease the effects of pergolide
Česta pitanja
What is Pergolide used for in pets?
> Important: Pergolide manages Equine Cushing's Disease (PPID) but does not cure it. Treatment is typically required for the rest of the horse's life. • Patience is Key: It may take several weeks to months to see noticeable improvements in your horse's hair coat, energy levels, and weight. • Appetite Changes: Some horses may eat less during the first week of treatment. If this happens, contact your veterinarian; a temporary dose reduction usually resolves the issue. • Storage Matters: If using a compounded liquid suspension, keep it in the refrigerator, protected from light. Discard it after 30 days or if it changes color, as the medication degrades quickly in water. • Holistic Care: Proper nutrition, regular farrier care, and weight management are crucial alongside medication for the successful treatment of this disease.
Is Pergolide safe for my pet?
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
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