Intravenous Fat Emulsion
يُعرف أيضًا باسم: Intralipid, Liposyn II, Liposyn III
Intravenous Fat Emulsion (IFE) is a specialized hospital-only treatment. * **For Poisonings:** It acts as a "sponge" in the bloodstream to soak up certain severe, life-threatening toxins (like heart medications, local anesthetics, or certain parasiticides). It can be a life-saving rescue therapy when standard treatments fail. * **For Nutrition:** It provides essential calories and fats for pets that cannot eat and require intravenous feeding. * Because it is given directly into the vein, your pet will require hospitalization, an IV catheter, and close monitoring by the veterinary team to watch for signs of infection or fat overload in the blood.
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
Veterinary professional? See the full dosing-by-species reference on VetSheet →
What it is used for
- Parenteral Nutrition (PN)
- Rescue agent for fat-soluble drug/toxin intoxication
- Parenteral Nutrition (PN)
- Rescue agent for fat-soluble drug/toxin intoxication
How it is given
Possible side effects
- Sepsis or thrombophlebitis (secondary to IV catheterization)
- Fat overload syndrome (hyperlipidemia, hepatomegaly, icterus, splenomegaly, fat embolism, thrombocytopenia, hemolysis, prolonged clotting times)
- Pulmonary toxicity (temporary)
- GI effects
- Somnolence
- Headache
- Flushing
- Pancreatitis
- Hypercoagulability
- Hypersensitivity
Cautions & contraindications
- Severe egg yolk allergies
- Abnormal fat metabolism
- Premature and low-birth weight infants (human black box warning)
- Blood coagulation disorders
- Pulmonary disease
- Renal impairment
- Severe liver damage
- Patients at high risk for fat emboli
- **Strict aseptic technique** and excellent IV catheter care are imperative to prevent sepsis. When used alone, IFE may be given via a peripheral line; when combined with amino acids/dextrose as Total Parenteral Nutrition (TPN), a dedicated central line is required due to hypertonicity. Use with caution in critically ill animals due to potential immunosuppression, exacerbation of pulmonary pathology, and increased infection rates. Blood samples for diagnostics should be drawn *prior* to administration to avoid severe lipemia artifacts (falsely high hemoglobin, MCH, MCHC, and altered bilirubin).
Drug interactions
- Lipid Soluble Drugs: IFE may act as a 'lipid sink', reducing the free circulating levels and clinical efficacy of concurrently administered lipophilic medications.
الأسئلة الشائعة
What is Intravenous Fat Emulsion used for in pets?
Intravenous Fat Emulsion (IFE) is a specialized hospital-only treatment. • For Poisonings: It acts as a "sponge" in the bloodstream to soak up certain severe, life-threatening toxins (like heart medications, local anesthetics, or certain parasiticides). It can be a life-saving rescue therapy when standard treatments fail. • For Nutrition: It provides essential calories and fats for pets that cannot eat and require intravenous feeding. • Because it is given directly into the vein, your pet will require hospitalization, an IV catheter, and close monitoring by the veterinary team to watch for signs of infection or fat overload in the blood.
Is Intravenous Fat Emulsion safe for my pet?
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
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