硫噴妥鈉
別名: Pentothal, Anesthal, Bensulf, Farmotal, Hipnopento, Inductal, Intraval, Nesdonal, Pensodital, Sandothal, Sodipental, Thionembutal, Thiopentax, Tiobarbital, Trapanal
藥物類別: Ultra-short acting thiobarbiturate anesthetic
硫噴妥是一種注射型麻醉劑，僅限由獸醫專業人員在醫院環境中使用。 * **監測：** 您的寵物在麻醉期間將受到密切監測，包括心跳速率、呼吸和血壓。 * **恢復：** 麻醉恢復可能需要幾個小時。某些品種（特別是靈緹犬和其他視覺獵犬）的恢復時間可能會顯著延長。 * **麻醉後護理：** 寵物回家後，請遵循獸醫關於餵食和活動的指示。
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
Veterinary professional? See the full dosing-by-species reference on VetSheet →
用途
- Anesthesia
- Anesthesia
- Anesthesia
- Anesthesia (unpremedicated)
- Anesthesia (after tranquilization)
- Anesthesia (after narcotic premedication)
- Anesthesia induction
- Anesthesia
- Deep surgical anesthesia (unweaned calves fasted 6-12h)
- Anesthesia (calves under 2 weeks of age)
- Anesthesia (after sedation and guaifenesin)
- Anesthesia (after tranquilization)
- Anesthesia (with preanesthetic tranquilization)
- Anesthesia (without preanesthetic tranquilization)
- Anesthesia (after xylazine or acepromazine)
- Anesthesia (after sedation and guaifenesin)
- Anesthesia (after tranquilization)
- Anesthesia
- Anesthesia (swine weighing 5-50 kg)
- Anesthesia (Rabbits)
- Anesthesia (Rabbits)
- Chemical restraint (Mice)
- Chemical restraint (Rats)
- Chemical restraint (Hamsters/Gerbils)
- Chemical restraint (Guinea pig)
- Chemical restraint (Rabbits)
- Anesthesia
- Brief anesthesia (7-10 minutes)
- Moderate anesthesia (10-15 minutes)
- Longer anesthesia (15-25 minutes)
- Anesthesia (unpremedicated)
- Anesthesia (after tranquilization)
- Anesthesia (after narcotic premedication)
- Anesthesia induction
給藥方式
IVIP
可能的副作用
- Ventricular bigeminy (dogs)
- Apnea (especially in cats)
- Arterial hypotension
- Excitement and severe ataxia during recovery (horses, if used alone)
- Transient leukopenia and hyperglycemia (horses)
- Vascular dilatation and hypoglycemia (with rapid IV administration)
- Severe tissue necrosis (if administered perivascularly)
- Prolonged recovery with repeated doses
注意事項與禁忌
- Absence of suitable veins for IV administration (Absolute)
- History of hypersensitivity to barbiturates (Absolute)
- Status asthmaticus (Absolute)
- Preexisting leukopenia in horses
- Use with extreme caution or avoid in greyhounds and other sight hounds
- Relative: Severe cardiovascular disease, ventricular arrhythmias, shock, increased intracranial pressure, myasthenia gravis, severe hepatic disease
- > **WARNING:** Thiopental is highly alkaline. Extravasation and intra-arterial injections must be strictly avoided to prevent severe tissue necrosis and CNS toxicity. * **Sight Hounds:** Greyhounds metabolize thiobarbiturates much more slowly; prolonged recoveries are common. Consider alternatives. * **Administration:** Give strictly to effect. Repeated doses accumulate and significantly prolong recovery. * **Dilution:** Do not use concentrations less than 2% in sterile water as they may cause hemolysis. * **Pregnancy:** Readily crosses the placental barrier; use with caution (FDA Category C).
藥物相互作用
- Clonidine: IV clonidine prior to induction may reduce thiopental dosage requirements by up to 37%
- CNS Depressants: May enhance respiratory and CNS depressant effects
- Diazoxide: Potential for hypotension
- Epinephrine / Norepinephrine: Ventricular fibrillatory effects may be potentiated when used with thiobarbiturates and halothane
- Metoclopramide: Given prior to induction may reduce thiopental dosage requirements
- Midazolam: May potentiate hypnotic effects
- Opiates: Given prior to induction may reduce thiopental dosage requirements
- Phenothiazines: May potentiate thiopental effects; hypotension possible
- Probenecid: May displace thiopental from plasma proteins
- Sulfonamides: Thiopental and sulfas may displace one another from plasma proteins
常見問題
硫噴妥鈉用於寵物有什麼用途？
硫噴妥是一種注射型麻醉劑，僅限由獸醫專業人員在醫院環境中使用。 • 監測： 您的寵物在麻醉期間將受到密切監測，包括心跳速率、呼吸和血壓。 • 恢復： 麻醉恢復可能需要幾個小時。某些品種（特別是靈緹犬和其他視覺獵犬）的恢復時間可能會顯著延長。 • 麻醉後護理： 寵物回家後，請遵循獸醫關於餵食和活動的指示。
硫噴妥鈉對我的寵物安全嗎？
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。