氯解磷定 (Pralidoxime Chloride)
別名: Protopam Chloride, 2-PAM
藥物類別: Antidote - Cholinesterase Reactivator
- **緊急治療：** 本藥物是針對特定類型農藥或神經毒劑（有機磷）中毒的關鍵救命解毒劑。 - **需要住院：** 您的寵物在接受此藥物治療期間，需要住院並由獸醫專業人員密切監測。 - **具時效性：** 此解毒劑在接觸毒物後越早給予效果越好（理想情況下在最初 24 小時內）。 - **合併治療：** 它幾乎總是與另一種稱為阿托品 (Atropine) 的解毒劑一起給予，以全面控制嚴重的中毒症狀。
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
Veterinary professional? See the full dosing-by-species reference on VetSheet →
用途
- Organophosphate poisoning
- Organophosphate poisoning
- Organophosphate poisoning
- Organophosphate poisoning
- Organophosphate poisoning
- Organophosphate poisoning
- Organophosphate poisoning
- Organophosphate poisoning
- Organophosphate poisoning
- Organophosphate poisoning
- Organophosphate poisoning
- Organophosphate poisoning
- Organophosphate poisoning
- Organophosphate poisoning
給藥方式
IVIMSCIP
可能的副作用
- Tachycardia (especially with rapid IV injection)
- Muscle rigidity
- Transient neuromuscular blockade
- Laryngospasm
注意事項與禁忌
- Hypersensitivity to pralidoxime
- Carbamate poisoning (generally not recommended as inhibition is rapidly reversible)
- Use with caution in patients receiving anticholinesterase agents for the treatment of myasthenia gravis, as it may precipitate a myasthenic crisis. Use cautiously and at a reduced dosage rate in patients with renal impairment. Must generally be given within 24 hours of exposure to be effective. Rapid IV injection should be avoided to prevent tachycardia, muscle rigidity, and laryngospasm.
藥物相互作用
- Barbiturates: Anticholinesterases can potentiate the action of barbiturates; use with caution.
- Cimetidine: Use should be avoided in patients with organophosphate toxicity.
- Succinylcholine: Use should be avoided in patients with organophosphate toxicity.
- Theophylline: Use should be avoided in patients with organophosphate toxicity.
- Reserpine: Use should be avoided in patients with organophosphate toxicity.
- Respiratory Depressants (e.g., narcotics, phenothiazines): Use should be avoided in patients with organophosphate toxicity.
常見問題
氯解磷定 (Pralidoxime Chloride)用於寵物有什麼用途？
- 緊急治療： 本藥物是針對特定類型農藥或神經毒劑（有機磷）中毒的關鍵救命解毒劑。 - 需要住院： 您的寵物在接受此藥物治療期間，需要住院並由獸醫專業人員密切監測。 - 具時效性： 此解毒劑在接觸毒物後越早給予效果越好（理想情況下在最初 24 小時內）。 - 合併治療： 它幾乎總是與另一種稱為阿托品 (Atropine) 的解毒劑一起給予，以全面控制嚴重的中毒症狀。
氯解磷定 (Pralidoxime Chloride)對我的寵物安全嗎？
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。