哌嗪
別名: Pipa-Tabs, Wazine, WormEze, D-Worm, Tasty Paste, Various AVM-GSL products
藥物類別: Antiparasitic - Anthelmintic
* **嚴格按照指示給藥**：請僅給予獸醫處方的劑量，切勿過量。 * **通常需要再次治療**：由於藥物只能殺死腸道內的成蟲，對組織中遷移的幼蟲無效，因此通常需要在首次給藥後 2 到 3 週進行第二次給藥。 * **監測副作用**：如果您發現任何嚴重的副作用，如嘔吐、腹瀉、嚴重虛弱、肌肉抽搐或步態不穩（共濟失調），請立即聯繫您的獸醫。
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Treatment of ascarids
- Treatment of ascarids
- Treatment of ascarids
- Treatment of ascarids
- Treatment of ascarids
- Treatment of ascarids
- Ascarids in poultry
- Nematodes in raptors
- Nematodes in parakeets and canaries
- Ascaridia galli in poultry
- Ascaris suum and Oesophagostomum
- Ascaris suum and Oesophagostomum
- Pinworms (Mice, rats, hamsters, gerbils, and rabbits)
- Pinworms (Rabbits)
給藥方式
PO
可能的副作用
- Diarrhea
- Emesis
- Ataxia
- Transient softening of feces (horses)
- Neurological signs at high doses (ataxia, tremors)
注意事項與禁忌
- Chronic liver disease
- Chronic kidney disease
- Gastrointestinal hypomotility
- Chronic renal failure
- Hepatic impairment
- Heavy worm burdens (relative contraindication due to risk of intestinal impaction)
- > **Important**: Use with caution in patients with seizure disorders. > **Equine Warning**: In horses with heavy infestations of *Parascaris equorum*, rupture or blockage of the intestines is possible due to the rapid death and detachment of a large worm burden. * **Laboratory Interference**: Piperazine can affect uric acid blood levels (both falsely high and low values have been reported); interpret results cautiously.
藥物相互作用
- Chlorpromazine: May precipitate seizures if used concomitantly (data conflicts, but caution is advised)
- Laxatives (Purgatives): Not recommended; may eliminate piperazine from the GI tract before its full efficacy is established
- Pyrantel / Morantel: Antagonistic modes of action (pyrantel causes spastic paralysis, piperazine causes flaccid paralysis); should not be used together
- Pyrantel: Antagonistic mechanism of action (Pyrantel causes spastic paralysis, Piperazine causes flaccid paralysis)
- Morantel: Antagonistic mechanism of action
常見問題
哌嗪用於寵物有什麼用途？
* **嚴格按照指示給藥**：請僅給予獸醫處方的劑量，切勿過量。 * **通常需要再次治療**：由於藥物只能殺死腸道內的成蟲，對組織中遷移的幼蟲無效，因此通常需要在首次給藥後 2 到 3 週進行第二次給藥。 * **監測副作用**：如果您發現任何嚴重的副作用，如嘔吐、腹瀉、嚴重虛弱、肌肉抽搐或步態不穩（共濟失調），請立即聯繫您的獸醫。
哌嗪對我的寵物安全嗎？
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。