美索比妥

用途

• Induction or sole anesthetic in non-premedicated cats
• Induction or sole anesthetic in premedicated cats
• Induction with premedication
• Induction or sole anesthetic in non-premedicated dogs
• Induction or sole anesthetic in premedicated dogs

給藥方式

可能的副作用

• Apnea
• Hypotension
• Muscle tremors
• Seizures during recovery
• Rough recoveries (especially in dogs)
• Profound respiratory depression
• Tissue necrosis (if extravasated)

注意事項與禁忌

• Absence of suitable veins for IV administration
• History of hypersensitivity reactions to barbiturates
• Status asthmaticus
• Cattle (due to unpredictable effects)
• > **WARNING**: Strictly for IV use. Perivascular extravasation causes severe tissue necrosis. Extravasation injuries can be treated with multiple infiltrates of sterile normal saline and lidocaine for pain. - **Relative Contraindications**: Seizure-prone animals, severe cardiovascular disease, preexisting ventricular arrhythmias, shock, increased intracranial pressure, myasthenia gravis, asthma, and conditions with prolonged hypnotic effects (e.g., severe hepatic disease, myxedema, severe anemia). - **Species Warnings**: NOT recommended for use in cattle due to unpredictable effects. - **Administration**: Repeated dosing or IV infusions are not recommended as recovery times can be significantly prolonged and increase the risk for complications.

藥物相互作用

• CNS Depressants (e.g., alpha2-agonists, opioids): Additive CNS and respiratory depression; premedication is usually preferred to reduce methohexital dosage required for inductions and to decrease rough recoveries.

常見問題