馬尿酸烏洛托品
別名: Hiprex, Urex
藥物類別: Urinary Antiseptic
* **給藥方式：** 請嚴格按照處方給藥。如果您的寵物出現腸胃不適（嘔吐或食慾不振），請嘗試在**飯後**給藥。 * **飲食的重要性：** 此藥物*僅在*寵物的尿液呈酸性時才有效。嚴格按照獸醫師的指示餵食任何特殊的處方飲食或給予尿液酸化劑是至關重要的。 * **依從性：** 請勿漏服。必須持續給藥以防止感染復發。 * **監測：** 您的獸醫師可能需要定期檢查您寵物的尿液 pH 值，以確保藥物正常發揮作用。
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
Veterinary professional? See the full dosing-by-species reference on VetSheet →
用途
- Urinary tract infection prophylaxis
- Urinary tract infection prophylaxis
- Urinary tract infection prophylaxis
- Urinary tract infection prophylaxis
給藥方式
PO
可能的副作用
- Gastrointestinal irritation (nausea, vomiting, anorexia)
- Dysuria (secondary to formaldehyde irritation with long-term use)
- Systemic acidosis (potential)
- Lipoid pneumonitis (reported in humans using oral suspension)
注意事項與禁忌
- Hypersensitivity to methenamine or its salts
- Renal insufficiency
- Metabolic acidosis
- Severe hepatic impairment (due to ammonia production during hydrolysis)
- Severe dehydration
- > **Crucial Efficacy Requirement:** Urine pH MUST be kept below 6.5 (ideally ≤ 5.5) for the drug to be effective. * **Urea-Splitting Bacteria:** Infections with urea-splitting organisms (e.g., *Proteus*, some *Staphylococcus*, *Pseudomonas*) naturally alkalinize the urine, potentially rendering methenamine ineffective. * **Acidification Therapy:** Concurrent use of urinary acidifiers (e.g., methionine, ammonium chloride, ascorbic acid) or prescription acidifying diets is often required. * **Species Sensitivity:** Cats reportedly do not tolerate methenamine as well as dogs. * **Pregnancy:** FDA Category C. Crosses the placenta; use with caution during pregnancy. Enters milk, but no adverse effects reported in nursing offspring.
藥物相互作用
- Sulfamethiazole: Not recommended; an insoluble precipitate may form in the urine.
- Urine Alkalinizing Drugs (e.g., calcium/magnesium antacids, carbonic anhydrase inhibitors, citrates, sodium bicarbonate, thiazide diuretics): May reduce the efficacy of methenamine by preventing its conversion to formaldehyde in the urine.
常見問題
馬尿酸烏洛托品用於寵物有什麼用途？
• 給藥方式： 請嚴格按照處方給藥。如果您的寵物出現腸胃不適（嘔吐或食慾不振），請嘗試在飯後給藥。 • 飲食的重要性： 此藥物*僅在*寵物的尿液呈酸性時才有效。嚴格按照獸醫師的指示餵食任何特殊的處方飲食或給予尿液酸化劑是至關重要的。 • 依從性： 請勿漏服。必須持續給藥以防止感染復發。 • 監測： 您的獸醫師可能需要定期檢查您寵物的尿液 pH 值，以確保藥物正常發揮作用。
馬尿酸烏洛托品對我的寵物安全嗎？
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。