氟伏沙明
別名: Luvox, Luvox CR, Dumirox, Faverin, Fevarin
藥物類別: Selective Serotonin-Reuptake Inhibitor (SSRI)
- **需要耐心**：此藥物不會立即見效。通常需要持續使用 6 到 8 週才能看到行為的顯著改善。 - **行為訓練**：當與專業的行為矯正計畫結合使用時，氟伏沙明最為有效。 - **副作用**：請注意食慾下降、嗜睡、嘔吐或異常行為（如焦慮增加或攻擊性）。如果您的寵物完全停止進食，請聯繫您的獸醫。 - **安全存放**：請將此藥物嚴格存放在兒童和其他寵物接觸不到的地方。 - **請勿突然停藥**：如果需要停止治療，您的獸醫將指導您如何逐漸減少劑量以避免戒斷症狀。
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
Veterinary professional? See the full dosing-by-species reference on VetSheet →
用途
- For treatment of compulsive disorders
- For treatment of behavioral diagnoses
- For spraying
- For treatment of behavioral diagnoses
- For treatment of compulsive disorders
- For treatment of behavioral diagnoses
- For treatment of behavioral diagnoses
給藥方式
PO
可能的副作用
- Anorexia/decreased appetite (common)
- Lethargy or sedation
- Gastrointestinal upset (vomiting, diarrhea)
- Anxiety, irritability, or agitation
- Insomnia or hyperactivity
- Panting (dogs)
- Changes in elimination patterns (cats)
- Paradoxical aggressive behavior in previously non-aggressive dogs
注意事項與禁忌
- Patients with known hypersensitivity to fluvoxamine or other SSRIs
- Concurrent use of Monoamine Oxidase Inhibitors (MAOIs) such as selegiline or amitraz
- Concurrent use of cisapride
- > **Caution:** Use with care in patients with severe cardiac, renal, or hepatic disease. Dosages may need to be reduced in patients with severe renal or hepatic impairment, or in geriatric patients. - **Pregnancy:** FDA Category C. Animal studies in rats showed increased pup mortality at birth and decreased birth weights. - **Lactation:** Fluvoxamine enters maternal milk, though it appears unlikely to be of significant clinical concern.
藥物相互作用
- Buspirone: Fluvoxamine may paradoxically decrease the clinical efficacy of buspirone.
- Cisapride: Fluvoxamine may increase plasma levels of cisapride, leading to toxicity. Concurrent use is contraindicated.
- Cyproheptadine: May decrease or reverse the effects of SSRIs (useful in treating serotonin syndrome).
- Diazepam, Alprazolam, Midazolam: Fluvoxamine may increase diazepam (and other benzodiazepine) levels.
- Diltiazem: Fluvoxamine may increase the effects of diltiazem; bradycardia has been reported in humans.
- MAO Inhibitors (e.g., amitraz, selegiline): High risk for serotonin syndrome; contraindicated. A 5-week washout is required after stopping fluvoxamine, and a 2-week washout if stopping the MAOI first.
- Methadone: Fluvoxamine may increase plasma levels of methadone, leading to toxicity.
- Phenytoin: Increased plasma levels of phenytoin possible.
- Propranolol, Metoprolol: Fluvoxamine may increase these beta-blockers' plasma levels; atenolol may be safer.
- Theophylline: Fluvoxamine may increase plasma levels of theophylline.
- Tramadol: SSRIs can inhibit the metabolism of tramadol to active metabolites, decreasing efficacy and increasing toxicity risk (serotonin syndrome, seizures).
- Tricyclic Antidepressants (e.g., clomipramine, amitriptyline): Fluvoxamine may increase TCA blood levels and increase the risk for serotonin syndrome.
- Warfarin: Fluvoxamine may increase the risk for bleeding.
常見問題
氟伏沙明用於寵物有什麼用途？
- 需要耐心：此藥物不會立即見效。通常需要持續使用 6 到 8 週才能看到行為的顯著改善。 - 行為訓練：當與專業的行為矯正計畫結合使用時，氟伏沙明最為有效。 - 副作用：請注意食慾下降、嗜睡、嘔吐或異常行為（如焦慮增加或攻擊性）。如果您的寵物完全停止進食，請聯繫您的獸醫。 - 安全存放：請將此藥物嚴格存放在兒童和其他寵物接觸不到的地方。 - 請勿突然停藥：如果需要停止治療，您的獸醫將指導您如何逐漸減少劑量以避免戒斷症狀。
氟伏沙明對我的寵物安全嗎？
劑量必須由獸醫依你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。