氟苯尼考

用途

• Susceptible systemic (bacterial or rickettsial) infections
• Swine respiratory disease
• Respiratory disease complex in kids
• Bovine respiratory disease (BRD)
• Bovine respiratory disease (BRD)
• Bovine respiratory disease (BRD)
• BRD and control of BRD-associated pyrexia
• Respiratory disease complex in kids
• Susceptible systemic (bacterial or rickettsial) infections
• Otitis externa (associated with Staphylococcus pseudintermedius and Malassezia pachydermatis)

給藥方式

可能的副作用

• Cattle: Anorexia, decreased water consumption, diarrhea
• Cattle: Injection site reactions (may result in trim loss)
• Cattle: Anaphylaxis and collapse (rare)
• Small Animals: Pain on IM injection
• Small Animals: Gastrointestinal effects, including severe diarrhea
• Mild application site erythema
• Head shaking
• Transient hearing loss (rare)
• Altered hearing or deafness in older dogs (rare)

注意事項與禁忌

• Intravenous (IV) administration
• Veal calves or preruminating calves
• Cattle or swine of breeding age (effects on reproduction unknown)
• Female dairy cattle 20 months of age or older
• Tympanic membrane rupture (perforated eardrum)
• Hypersensitivity to florfenicol, terbinafine, or betamethasone
• Dogs with generalized demodicosis (due to corticosteroid component)
• > **Important Administration Warning:** Do NOT administer intravenously (IV). * **Injection Site:** In cattle, injections should be given *only* in the neck muscle to minimize trim loss and severe tissue reactions. * **Volume Limits:** Do not exceed 10 mL (or 15 mL for Nuflor Gold) per injection site in cattle. * **Residue Warnings:** Strict adherence to slaughter withdrawal times is legally required for food-producing animals. Do not use in female dairy cattle ≥20 months of age or in veal calves. * **Reproductive Safety:** Safety in breeding, pregnant, or lactating animals has not been established.

藥物相互作用

• Penicillins: May antagonize the bactericidal activity of penicillins (theoretical, though often used together clinically).
• Aminoglycosides: May antagonize the bactericidal activity of aminoglycosides.
• Macrolides (e.g., erythromycin, tylosin): May potentially antagonize activity due to competition for binding at the 50S ribosomal subunit.
• Lincosamides (e.g., clindamycin, lincomycin): May potentially antagonize activity due to competition for binding at the 50S ribosomal subunit.

常見問題