Robenacoxib
別名: Onsior
**Onsior® (Robenacoxib)** is a medication used to relieve pain and inflammation in your pet. To ensure it works safely and effectively, please follow these guidelines: * **For Dogs**: Give the tablet on an empty stomach. Administer it at least 30 minutes before or after a meal. * **For Cats**: You can give the tablet with or without a small amount of food. **Do not divide, break, or crush the tablets**. * **Handling**: Wash your hands after handling the medication. Pregnant women who are near term should wear gloves when handling this drug. * **What to Watch For**: Stop giving the medication and contact your veterinarian immediately if your pet shows any signs of illness, such as: * Severe or bloody vomiting or diarrhea * Loss of appetite or extreme lethargy (listlessness) * Yellowing of the whites of the eyes or gums (jaundice) * Collapse or weakness * **Never** give your pet any other pain medications (like aspirin, ibuprofen, or other veterinary NSAIDs) or steroids while they are taking this drug without consulting your veterinarian.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Acute pain and inflammation associated with musculoskeletal disorders
- Pain and inflammation associated with chronic osteoarthritis (Note: Label likely intended for surgical pain based on injection formulation)
- Perioperative analgesia
- Acute and chronic musculoskeletal pain and inflammation
- Pain and inflammation associated with chronic osteoarthritis
- Pain and inflammation associated with orthopedic or soft tissue surgery
- Perioperative analgesia (orthopaedic and soft tissue surgery)
- Acute and chronic musculoskeletal disorders
給藥方式
可能的副作用
- Decreased appetite
- Vomiting
- Soft feces
- Diarrhea
- Blood in feces (melena/hematochezia)
- Mild gastrointestinal signs (vomiting, soft feces, diarrhea)
- Gastrointestinal ulceration or bleeding (rare but severe)
- Renal toxicity (especially if hypotensive or dehydrated)
- Hepatic accumulation (in patients with pre-existing liver disease)
注意事項與禁忌
- Patients with active gastrointestinal ulcers
- Hypersensitivity to robenacoxib or its excipients
- Dogs with hepatic disease
- Dehydrated, hypovolaemic, or hypotensive patients
- Patients with pre-existing gastrointestinal disease or ulceration
- Patients with blood clotting disorders
- Pregnant or lactating animals
- Dogs < 12 weeks of age or < 2.5 kg body weight
- Cats < 16 weeks of age or < 2.5 kg body weight
- Perioperative use in animals with renal disease (not advisable)
- > **Strict Veterinary Monitoring Required**: Use with extreme caution in patients with impaired cardiac or renal function, dehydration, hypovolemia, hypotension, or in cats with hepatic dysfunction. * **Washout Period**: Do not use concurrently with corticosteroids or other NSAIDs. A treatment-free period of at least 24 hours (accounting for the half-life of the previous drug) should be observed before starting robenacoxib. * **Renal Perfusion**: Use cautiously with drugs that affect renal blood flow (e.g., diuretics, ACE inhibitors) due to the risk of renal toxicity. * **Reproduction**: Safety has not been established in pregnant or lactating animals; use is not recommended.
藥物相互作用
- ACE Inhibitors (e.g., enalapril, benazepril): Some NSAIDs can reduce effects on blood pressure
- Aspirin: May increase the risk of gastrointestinal toxicity (e.g., ulceration, bleeding, vomiting, diarrhea)
- Corticosteroids (e.g., prednisone): May increase the risk of gastrointestinal toxicity (e.g., ulceration, bleeding, vomiting, diarrhea)
- Digoxin: NSAIDs may increase serum levels
- Fluconazole: Administration has increased plasma levels of celecoxib in humans and potentially could also affect robenacoxib levels in dogs
- Furosemide: NSAIDs may reduce the saluretic and diuretic effects
- Highly Protein Bound Drugs (phenytoin, valproic acid, oral anticoagulants, salicylates, sulfonamides, etc.): As robenacoxib is highly bound to plasma proteins (>99%), it may displace other highly bound drugs or be displaced by them, potentially leading to increased serum levels and toxicity
- Methotrexate: Serious toxicity has occurred when NSAIDs have been used concomitantly; use together with extreme caution
- Nephrotoxic Drugs (e.g., aminoglycosides, amphotericin B): May enhance the risk of nephrotoxicity development
常見問題
Robenacoxib用於寵物有甚麼用途？
**Onsior® (Robenacoxib)** is a medication used to relieve pain and inflammation in your pet. To ensure it works safely and effectively, please follow these guidelines: * **For Dogs**: Give the tablet on an empty stomach. Administer it at least 30 minutes before or after a meal. * **For Cats**: You can give the tablet with or without a small amount of food. **Do not divide, break, or crush the tablets**. * **Handling**: Wash your hands after handling the medication. Pregnant women who are near term should wear gloves when handling this drug. * **What to Watch For**: Stop giving the medication and contact your veterinarian immediately if your pet shows any signs of illness, such as: * Severe or bloody vomiting or diarrhea * Loss of appetite or extreme lethargy (listlessness) * Yellowing of the whites of the eyes or gums (jaundice) * Collapse or weakness * **Never** give your pet any other pain medications (like aspirin, ibuprofen, or other veterinary NSAIDs) or steroids while they are taking this drug without consulting your veterinarian.
Robenacoxib對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。