Oseltamivir
別名: Tamiflu
- **Experimental Use:** If prescribed for your pet (such as for parvovirus), understand that this is an experimental, "off-label" use of a human medication. - **Administration:** It is crucial to give this medication exactly as prescribed. If your pet is vomiting, your veterinarian may recommend giving an anti-nausea injection about 30 minutes before giving this oral medication to help them keep it down. - **Side Effects:** The most common side effect is mild stomach upset (nausea or vomiting). Giving the medication with a small amount of food may help reduce this. - **Public Health:** This drug is the same as human Tamiflu®. Its use in pets is controversial because it is an important drug for human flu pandemics.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Treatment of equine Influenza A
- Adjunctive treatment of canine parvovirus enteritis
- Adjunctive treatment of canine parvovirus enteritis
給藥方式
可能的副作用
- Gastrointestinal upset (nausea, vomiting - usually transient)
- Insomnia (reported in humans)
- Vertigo (reported in humans)
注意事項與禁忌
- Known hypersensitivity to oseltamivir
- Poultry (chickens, turkeys, ducks) - FDA banned for extra-label use
- > **Public Health & Ethical Considerations:** Routine use in dogs and cats is discouraged to prevent viral resistance and preserve human stockpiles for pandemic influenza. - **Timing:** For true influenza infections, treatment must begin as early as possible (ideally within 40-48 hours of clinical signs onset) to be effective. - **Renal Impairment:** Dosages may need adjustment in patients with severe renal insufficiency, as the active metabolite is primarily renally excreted. - **Neonatal Toxicity:** High doses in neonatal rats showed significant accumulation in the brain compared to adults. Use with extreme caution in newborn puppies or kittens due to potential **neurotoxicity**. - **Pregnancy:** FDA Category C. Minor skeletal abnormalities noted in high-dose rabbit studies. Use only if benefits outweigh risks.
藥物相互作用
- Probenecid: May increase 2-fold the exposure to oseltamivir carboxylate (active metabolite) by reducing renal tubular secretion.
- Vaccines, influenza (live): May potentially reduce the immune response to live influenza virus vaccines. No effect on inactivated (killed) vaccines.
常見問題
Oseltamivir用於寵物有甚麼用途？
- **Experimental Use:** If prescribed for your pet (such as for parvovirus), understand that this is an experimental, "off-label" use of a human medication. - **Administration:** It is crucial to give this medication exactly as prescribed. If your pet is vomiting, your veterinarian may recommend giving an anti-nausea injection about 30 minutes before giving this oral medication to help them keep it down. - **Side Effects:** The most common side effect is mild stomach upset (nausea or vomiting). Giving the medication with a small amount of food may help reduce this. - **Public Health:** This drug is the same as human Tamiflu®. Its use in pets is controversial because it is an important drug for human flu pandemics.
Oseltamivir對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。