Gemcitabine
別名: Gemzar, Abine, Antoril, Gemcite, Gemtrol
- **Investigational Therapy**: Understand that veterinary experience with gemcitabine is limited, and it must be considered an 'investigational' treatment. - **Safety Precautions**: Gemcitabine is a hazardous chemotherapy drug. **Drug residues can be detected in your pet's urine for up to 7 days** after a dose. - Always wear **disposable gloves** when cleaning up urine, feces, or vomit from treated pets. - **Monitoring**: Your pet will need frequent blood tests to monitor white blood cell and platelet counts, as this drug can suppress the bone marrow. Watch for signs of lethargy, bruising, or gastrointestinal upset.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Carcinomas (in combination with carboplatin)
- Exocrine pancreatic carcinoma (Low dose)
- Carcinomas (in combination with carboplatin)
- Bladder urothelial carcinoma, lymphoma, and various carcinomas (High dose)
- Bladder urothelial carcinoma, lymphoma, and various carcinomas (Low dose)
- Carcinomas (Combination therapy)
- Advanced solid tumors
給藥方式
可能的副作用
- Myelosuppression (neutropenia and thrombocytopenia; nadir at 3-7 days)
- Mild to moderate gastrointestinal toxicity
- Retinal hemorrhage
- Myelosuppression (neutropenia, thrombocytopenia, anemia)
- Gastrointestinal toxicity (vomiting, diarrhea, anorexia)
- Retinal haemorrhage
- Treatment-related mortality (due to severe complications)
注意事項與禁忌
- Hypersensitivity to gemcitabine
- Known hypersensitivity to gemcitabine
- Pre-existing bone marrow suppression
- Use with caution in patients with diminished renal or hepatic function. FDA Category D for pregnancy (evidence of fetal risk). Handle with standard cytotoxic safety precautions.
藥物相互作用
- Other myelosuppressive agents: Additive toxic effects (myelosuppression, GI toxicity)
常見問題
Gemcitabine用於寵物有甚麼用途？
- **Investigational Therapy**: Understand that veterinary experience with gemcitabine is limited, and it must be considered an 'investigational' treatment. - **Safety Precautions**: Gemcitabine is a hazardous chemotherapy drug. **Drug residues can be detected in your pet's urine for up to 7 days** after a dose. - Always wear **disposable gloves** when cleaning up urine, feces, or vomit from treated pets. - **Monitoring**: Your pet will need frequent blood tests to monitor white blood cell and platelet counts, as this drug can suppress the bone marrow. Watch for signs of lethargy, bruising, or gastrointestinal upset.
Gemcitabine對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。