Folic Acid
別名: Folvite, Deplin
- **Purpose:** Folic acid is a B-vitamin used to treat deficiencies often caused by chronic intestinal diseases, pancreatic issues, or long-term use of certain antibiotics. - **Safety:** It is a very safe supplement. Because it is water-soluble, the body easily eliminates any excess in the urine. - **Administration:** Can be given with or without food. Follow your veterinarian's instructions carefully. - **Long-term Care:** If your pet has chronic intestinal disease or pancreatic insufficiency, lifelong monitoring of vitamin levels and periodic replacement therapy may be required to keep them healthy.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Severe folate deficiency
- Folate deficiency secondary to exocrine pancreatic insufficiency
- Long-term use of high dose trimethoprim/sulfa (for treating Nocardia)
- Adjunctive therapy in cats with inflammatory bowel disease
- Prolonged therapy with antifolate medications (e.g., trimethoprim, pyrimethamine)
- Severe folate deficiency
- Folate and cobalamin deficiency secondary to inflammatory bowel disease
給藥方式
可能的副作用
- Hypersensitivity reactions (rare)
- Gastrointestinal effects (rare)
- CNS effects such as difficulty sleeping, excitement, or confusion (seen only at very high oral doses in humans, e.g., 15 mg/day)
注意事項與禁忌
- Known intolerance or hypersensitivity to folic acid
- Undiagnosed anemias (folic acid therapy may mask the hematologic signs of pernicious anemia/cobalamin deficiency while neurologic damage progresses)
- > **Important:** Do not administer therapeutic doses of folic acid to dogs with enteropathies until baseline serum folate and cobalamin levels have been determined, as dogs may have increased, normal, or decreased folate levels depending on the specific disease process (e.g., bacterial overgrowth vs. malabsorption). - Prolonged folic acid supplementation can potentially decrease serum cobalamin (B-12) levels. - Folic acid is considered very safe during pregnancy (FDA Category A) and lactation. Requirements may actually increase in lactating animals.
藥物相互作用
- Chloramphenicol: May delay the hematologic response to folic acid.
- Methotrexate: Inhibits dihydrofolate reductase; interferes with folic acid utilization.
- Trimethoprim: Inhibits dihydrofolate reductase; interferes with folic acid utilization.
- Pyrimethamine: Inhibits dihydrofolate reductase; interferes with folic acid utilization.
- Phenytoin: Folic acid may decrease serum phenytoin levels, potentially requiring a dosage increase; increased seizure frequency can occur.
- Sulfasalazine: May increase the risk for folate deficiency.
- Barbiturates: May increase the risk for folate deficiency.
- Nitrofurantoin: May increase the risk for folate deficiency.
- Primidone: May increase the risk for folate deficiency.
常見問題
Folic Acid用於寵物有甚麼用途？
- **Purpose:** Folic acid is a B-vitamin used to treat deficiencies often caused by chronic intestinal diseases, pancreatic issues, or long-term use of certain antibiotics. - **Safety:** It is a very safe supplement. Because it is water-soluble, the body easily eliminates any excess in the urine. - **Administration:** Can be given with or without food. Follow your veterinarian's instructions carefully. - **Long-term Care:** If your pet has chronic intestinal disease or pancreatic insufficiency, lifelong monitoring of vitamin levels and periodic replacement therapy may be required to keep them healthy.
Folic Acid對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。