Flumethasone
別名: Flucort, Cerson, Locacorten, Locacortene, Locorten, Locortene, Lorinden
Flumethasone is a potent steroid medication used to rapidly reduce inflammation, treat severe allergies, or manage certain skin and joint conditions. * **Follow Instructions Carefully**: Give the exact dose prescribed. **Do not stop this medication abruptly** without consulting your veterinarian, as sudden withdrawal can cause a life-threatening crisis due to the body's temporary inability to produce its own natural steroids. * **Expected Side Effects**: You may notice your pet drinking more water, urinating more frequently, and having an increased appetite. Panting is also common in dogs. * **When to Call the Vet**: Contact your veterinarian if side effects become severe, if your pet develops vomiting, diarrhea, dark/tarry stools (a sign of stomach ulcers), extreme lethargy, or behavioral changes (like unusual aggression or depression). * **Immune System**: Because this drug suppresses the immune system, keep your pet away from sick animals and consult your vet before any vaccinations.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Labeled indications (acute and chronic dermatoses)
- Labeled indications (acute and chronic dermatoses)
- General anti-inflammatory/immunosuppressive
- Labeled indications (musculoskeletal conditions, allergic states)
- General anti-inflammatory
- Labeled indications (musculoskeletal conditions, dermatoses, allergic states, shock)
- Labeled indications
- Labeled indications (joint inflammation)
- Labeled indications (localized lesions)
- General anti-inflammatory/immunosuppressive
給藥方式
可能的副作用
- Polydipsia (PD), polyuria (PU), and polyphagia (PP)
- Weight gain and lipidemias
- Dull, dry haircoat and dermatological thinning
- Panting
- Gastrointestinal effects: vomiting, diarrhea, GI ulceration
- Hepatopathy: elevated liver enzymes (ALP, ALT)
- Pancreatitis
- Endocrine: activation or worsening of diabetes mellitus, iatrogenic hyperadrenocorticism (Cushingoid effects) with sustained use
- Musculoskeletal: muscle wasting, retarded growth in young animals
- Behavioral changes: depression, lethargy, viciousness
- Immunosuppression: increased susceptibility to infections
注意事項與禁忌
- Last trimester of pregnancy (may induce parturition)
- Systemic fungal infections (unless used for Addison's replacement therapy)
- Idiopathic thrombocytopenia (specifically contraindicated for IM administration)
- Known hypersensitivity to the compound
- Chronic corticosteroid therapy of systemic diseases using sustained-release injectable forms
- **Tapering Required**: Animals that have received systemic glucocorticoids (other than short 'burst' therapy) must be tapered off slowly to allow endogenous ACTH and corticosteroid function to recover. **Stress Dosing**: If an animal undergoes a 'stressor' (e.g., surgery, trauma, illness) during the tapering process or before normal adrenal/pituitary function resumes, additional glucocorticoids should be administered. **Pregnancy Warning**: Corticosteroid therapy may induce parturition in large animal species during the latter stages of pregnancy. Categorized as Class C for canine and feline pregnancy (use cautiously as a last resort when benefits clearly outweigh risks).
藥物相互作用
- Amphotericin B: Administered concomitantly with glucocorticoids may cause hypokalemia
- Anticholinesterase agents (e.g., pyridostigmine, neostigmine): In patients with myasthenia gravis, concomitant administration may lead to profound muscle weakness. Discontinue anticholinesterase at least 24 hours prior if possible.
- Aspirin: Glucocorticoids may reduce salicylate blood levels
- Barbiturates: May increase the metabolism of glucocorticoids and decrease flumethasone blood levels
- Cyclophosphamide: Glucocorticoids may inhibit the hepatic metabolism of cyclophosphamide; dosage adjustments may be required
- Cyclosporine: Concomitant administration may increase the blood levels of each by mutually inhibiting hepatic metabolism
- Diazepam: Flumethasone may decrease diazepam levels
- Diuretics, potassium-depleting (e.g., spironolactone, triamterene): Administered concomitantly with glucocorticoids may cause hypokalemia
- Ephedrine: May reduce flumethasone blood levels
- Insulin: Insulin requirements may increase in patients receiving glucocorticoids
常見問題
Flumethasone用於寵物有甚麼用途？
Flumethasone is a potent steroid medication used to rapidly reduce inflammation, treat severe allergies, or manage certain skin and joint conditions. * **Follow Instructions Carefully**: Give the exact dose prescribed. **Do not stop this medication abruptly** without consulting your veterinarian, as sudden withdrawal can cause a life-threatening crisis due to the body's temporary inability to produce its own natural steroids. * **Expected Side Effects**: You may notice your pet drinking more water, urinating more frequently, and having an increased appetite. Panting is also common in dogs. * **When to Call the Vet**: Contact your veterinarian if side effects become severe, if your pet develops vomiting, diarrhea, dark/tarry stools (a sign of stomach ulcers), extreme lethargy, or behavioral changes (like unusual aggression or depression). * **Immune System**: Because this drug suppresses the immune system, keep your pet away from sick animals and consult your vet before any vaccinations.
Flumethasone對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。