氟米松
別名: Flucort, Cerson, Locacorten, Locacortene, Locorten, Locortene, Lorinden
藥物類別: Glucocorticoid
氟米松是一種強效類固醇藥物，用於快速減輕發炎、治療嚴重過敏或控制某些皮膚和關節疾病。 * **請仔細遵循指示**：請給予獸醫處方的準確劑量。**未經獸醫同意，請勿突然停藥**，因為突然停藥可能會導致身體暫時無法產生自身的天然類固醇，從而引發危及生命的危機。 * **預期的副作用**：您可能會注意到寵物喝水量增加、排尿更頻繁且食慾增加。狗也常出現喘氣的現象。 * **何時應聯繫獸醫**：如果副作用變得嚴重，或者您的寵物出現嘔吐、腹瀉、排出黑色/柏油狀糞便（胃潰瘍的徵兆）、極度嗜睡或行為改變（如異常的攻擊性或抑鬱），請立即聯繫您的獸醫。 * **免疫系統**：因為這種藥物會抑制免疫系統，請讓您的寵物遠離生病的動物，並在進行任何疫苗接種前諮詢您的獸醫。
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
Veterinary professional? See the full dosing-by-species reference on VetSheet →
用途
- Labeled indications (acute and chronic dermatoses)
- Labeled indications (acute and chronic dermatoses)
- General anti-inflammatory/immunosuppressive
- Labeled indications (musculoskeletal conditions, allergic states)
- General anti-inflammatory
- Labeled indications (musculoskeletal conditions, dermatoses, allergic states, shock)
- Labeled indications
- Labeled indications (joint inflammation)
- Labeled indications (localized lesions)
- General anti-inflammatory/immunosuppressive
給藥方式
POIMIVSCIntra-articularIntra-lesional
可能的副作用
- Polydipsia (PD), polyuria (PU), and polyphagia (PP)
- Weight gain and lipidemias
- Dull, dry haircoat and dermatological thinning
- Panting
- Gastrointestinal effects: vomiting, diarrhea, GI ulceration
- Hepatopathy: elevated liver enzymes (ALP, ALT)
- Pancreatitis
- Endocrine: activation or worsening of diabetes mellitus, iatrogenic hyperadrenocorticism (Cushingoid effects) with sustained use
- Musculoskeletal: muscle wasting, retarded growth in young animals
- Behavioral changes: depression, lethargy, viciousness
- Immunosuppression: increased susceptibility to infections
注意事項與禁忌
- Last trimester of pregnancy (may induce parturition)
- Systemic fungal infections (unless used for Addison's replacement therapy)
- Idiopathic thrombocytopenia (specifically contraindicated for IM administration)
- Known hypersensitivity to the compound
- Chronic corticosteroid therapy of systemic diseases using sustained-release injectable forms
- **Tapering Required**: Animals that have received systemic glucocorticoids (other than short 'burst' therapy) must be tapered off slowly to allow endogenous ACTH and corticosteroid function to recover. **Stress Dosing**: If an animal undergoes a 'stressor' (e.g., surgery, trauma, illness) during the tapering process or before normal adrenal/pituitary function resumes, additional glucocorticoids should be administered. **Pregnancy Warning**: Corticosteroid therapy may induce parturition in large animal species during the latter stages of pregnancy. Categorized as Class C for canine and feline pregnancy (use cautiously as a last resort when benefits clearly outweigh risks).
藥物相互作用
- Amphotericin B: Administered concomitantly with glucocorticoids may cause hypokalemia
- Anticholinesterase agents (e.g., pyridostigmine, neostigmine): In patients with myasthenia gravis, concomitant administration may lead to profound muscle weakness. Discontinue anticholinesterase at least 24 hours prior if possible.
- Aspirin: Glucocorticoids may reduce salicylate blood levels
- Barbiturates: May increase the metabolism of glucocorticoids and decrease flumethasone blood levels
- Cyclophosphamide: Glucocorticoids may inhibit the hepatic metabolism of cyclophosphamide; dosage adjustments may be required
- Cyclosporine: Concomitant administration may increase the blood levels of each by mutually inhibiting hepatic metabolism
- Diazepam: Flumethasone may decrease diazepam levels
- Diuretics, potassium-depleting (e.g., spironolactone, triamterene): Administered concomitantly with glucocorticoids may cause hypokalemia
- Ephedrine: May reduce flumethasone blood levels
- Insulin: Insulin requirements may increase in patients receiving glucocorticoids
- Ketoconazole and other azole antifungals: May decrease the metabolism of glucocorticoids and increase flumethasone blood levels; ketoconazole may induce adrenal insufficiency when glucocorticoids are withdrawn
- Macrolide antibiotics (erythromycin, clarithromycin): May decrease the metabolism of glucocorticoids and increase flumethasone blood levels
- Mitotane: May alter the metabolism of steroids; higher than usual doses of steroids may be necessary to treat mitotane-induced adrenal insufficiency
- NSAIDs: Administration of ulcerogenic drugs with glucocorticoids may increase the risk of gastrointestinal ulceration
- Phenytoin: May increase the metabolism of glucocorticoids and decrease flumethasone blood levels
- Rifampin: May increase the metabolism of glucocorticoids and decrease flumethasone blood levels
- Vaccines: Patients receiving immunosuppressive dosages should not receive live attenuated-virus vaccines (augmented virus replication); diminished immune response may occur with any vaccine
常見問題
氟米松用於寵物有甚麼用途？
氟米松是一種強效類固醇藥物，用於快速減輕發炎、治療嚴重過敏或控制某些皮膚和關節疾病。 • 請仔細遵循指示：請給予獸醫處方的準確劑量。未經獸醫同意，請勿突然停藥，因為突然停藥可能會導致身體暫時無法產生自身的天然類固醇，從而引發危及生命的危機。 • 預期的副作用：您可能會注意到寵物喝水量增加、排尿更頻繁且食慾增加。狗也常出現喘氣的現象。 • 何時應聯繫獸醫：如果副作用變得嚴重，或者您的寵物出現嘔吐、腹瀉、排出黑色/柏油狀糞便（胃潰瘍的徵兆）、極度嗜睡或行為改變（如異常的攻擊性或抑鬱），請立即聯繫您的獸醫。 • 免疫系統：因為這種藥物會抑制免疫系統，請讓您的寵物遠離生病的動物，並在進行任何疫苗接種前諮詢您的獸醫。
氟米松對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。