Dolasetron
別名: Anzemet, Anemet, Zamanon
> **What is Dolasetron?** Dolasetron is a strong anti-nausea medication, most commonly used to prevent or treat severe vomiting associated with chemotherapy in pets. * **Administration**: The injectable form is usually given by your veterinarian at the clinic. If you are sent home with oral medication, it will likely be specially compounded (remade into a smaller pill or liquid) by a pharmacy, as the standard human tablets are too large for dogs and cats. * **Side Effects**: This medication is generally very well tolerated by pets. * **When to call the vet**: Contact your veterinarian if your pet continues to vomit despite the medication, or if you notice extreme lethargy, weakness, or collapse.
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
用途
- Anti-emetic, particularly for patients receiving chemotherapeutics
- Vomiting disorders
- Prevent vomiting
- Treat vomiting
- General anti-emetic
- Anti-emetic, particularly for patients receiving chemotherapeutics
- General anti-emetic
- Vomiting disorders
- Prevent vomiting
- Treat vomiting
給藥方式
可能的副作用
- Dose-related ECG interval prolongation (PR, QTc, JT prolongation, and QRS widening)
- Headache (reported in humans)
- Dizziness (reported in humans)
注意事項與禁忌
- Known hypersensitivity to dolasetron
- Atrioventricular (AV) block II to III
- Markedly prolonged QTc interval
- Use with extreme caution in patients susceptible to cardiac conduction interval prolongation. This includes patients with hypokalemia, hypomagnesemia, congenital QT syndrome, those receiving anti-arrhythmic drugs or diuretics that induce electrolyte abnormalities, or those who have received a cumulative high dose of anthracycline chemotherapy. Note that 5-HT3 antagonists are generally ineffective for vomiting associated with feline hepatic lipidosis or mechanical GI obstruction.
藥物相互作用
- Atenolol: May reduce the clearance and increase blood levels of hydrodolasetron
- Cimetidine: May reduce the clearance and increase blood levels of hydrodolasetron
- Ketoconazole: May reduce the clearance and increase blood levels of hydrodolasetron
- Phenobarbital: Can reduce hydrodolasetron blood levels
- Rifampin: Can reduce hydrodolasetron blood levels
常見問題
Dolasetron用於寵物有甚麼用途？
> **What is Dolasetron?** Dolasetron is a strong anti-nausea medication, most commonly used to prevent or treat severe vomiting associated with chemotherapy in pets. * **Administration**: The injectable form is usually given by your veterinarian at the clinic. If you are sent home with oral medication, it will likely be specially compounded (remade into a smaller pill or liquid) by a pharmacy, as the standard human tablets are too large for dogs and cats. * **Side Effects**: This medication is generally very well tolerated by pets. * **When to call the vet**: Contact your veterinarian if your pet continues to vomit despite the medication, or if you notice extreme lethargy, weakness, or collapse.
Dolasetron對我的寵物安全嗎？
劑量必須由獸醫按你寵物的個別情況決定。切勿在沒有獸醫指導下給予人類藥物或其他寵物的處方藥。
本文僅供一般健康教育，不能取代專業獸醫意見。如寵物身體不適，請諮詢獸醫。