Nitazoxanide
Más néven: Alinia, Navigator, Daxon, Heliton
> **Important Note for Pet Owners**: Nitazoxanide is not commonly used in dogs and cats, and is considered an 'off-label' treatment in veterinary medicine. * **Side Effects**: In dogs and cats, this medication can cause significant stomach upset, including excessive drooling (hypersalivation), vomiting, and diarrhea. If these occur, contact your veterinarian, as the medication may need to be stopped. * **Administration**: Follow your veterinarian's exact dosing instructions. Do not adjust the dose without consulting them. * **Monitoring**: Keep an eye on your pet's appetite, energy levels, and body weight during treatment.
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
Veterinary professional? See the full dosing-by-species reference on VetSheet →
What it is used for
- Cryptosporidia-associated diarrhea
- Equine protozoal myeloencephalitis (EPM) caused by Sarcocystis neurona
- Relapsing EPM
How it is given
Possible side effects
- Horses: Fever, anorexia, lethargy/depression, decreased gut sounds, diarrhea/enterocolitis, colic, laminitis, head/limb edema
- Horses: 'Treatment crisis' (CNS inflammation secondary to dying protozoa)
- Dogs: Excessive salivation, vomiting, diarrhea (often therapy-limiting)
- Humans: Yellow discoloration of sclera (rare, reversible)
Cautions & contraindications
- Horses less than 1 year of age
- Horses that are sick or debilitated for reasons other than EPM
- Use with extreme caution in stallions and horses predisposed to laminitis
- Animals with compromised renal or hepatic function (safety not established)
- Use with caution in animals with compromised renal or hepatic function. In horses, monitor closely for signs of enterocolitis (disruption of normal flora) and laminitis (stallions may be more prone). A 'treatment crisis' may occur in horses during the first two weeks of EPM therapy due to CNS inflammation from dying protozoa, which may require anti-inflammatory therapy. Not evaluated in horses weighing > 1200 lbs.
Drug interactions
- Highly protein-bound drugs with narrow therapeutic index: Use with caution; tizoxanide is >99% protein bound and may displace or be displaced by other highly bound drugs, potentially altering free drug concentrations.
Gyakori kérdések
What is Nitazoxanide used for in pets?
> Important Note for Pet Owners: Nitazoxanide is not commonly used in dogs and cats, and is considered an 'off-label' treatment in veterinary medicine. • Side Effects: In dogs and cats, this medication can cause significant stomach upset, including excessive drooling (hypersalivation), vomiting, and diarrhea. If these occur, contact your veterinarian, as the medication may need to be stopped. • Administration: Follow your veterinarian's exact dosing instructions. Do not adjust the dose without consulting them. • Monitoring: Keep an eye on your pet's appetite, energy levels, and body weight during treatment.
Is Nitazoxanide safe for my pet?
Dosage must be set by your veterinarian for your specific pet. Never give human medication or another pet’s prescription without veterinary guidance.
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